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产品名称
小鼠瘦素ELISA, This Mouse Leptin ELISA is used to measure & quantify Leptin levels in Metabolism & Endocrine & Neuroscience research.
质量水平
种属反应性
mouse
包装
kit of 1 × 96 wells
参数
10 μL sample volume (4hr assay)
assay range
accuracy: 87-100%
linearity: 100-111%
sensitivity: 0.05 ng/mL
standard curve range: 0.2-30 ng/mL
技术
ELISA: suitable
输入
sample type serum
sample type plasma (K2 EDTA)
应用
research use
检测方法
colorimetric (450nm/590nm)
运输
wet ice
储存温度
2-8°C
一般描述
小鼠瘦素ELISA试剂盒用于测定代谢、内分泌和神经科学研究中的瘦素水平。瘦素是一种由脂肪细胞分泌在血液中循环的激素或细胞因子。通过下丘脑作用调节食物摄取和能量消耗。也在血管生成、脂质和糖类代谢、造血过程中起作用。瘦素可作用于心血管、生殖和免疫系统。在啮齿动物中，瘦素缺乏与肥胖和胰岛素抵抗相关。
应用
小鼠瘦素ELISA试剂盒已用于测定小鼠血清和血浆中的瘦素水平。
免责声明
仅供研究使用。不用于诊断操作。
警示用语：
Warning
危险声明
危险分类
Met. Corr. 1 - Skin Sens. 1
储存分类代码
8A - Combustible corrosive hazardous materials
Timothy M Griffin et al.
Arthritis and rheumatism, 60(10), 2935-2944 (2009-10-01)
To test the hypothesis that obesity resulting from deletion of the leptin gene or the leptin receptor gene results in increased knee osteoarthritis (OA), systemic inflammation, and altered subchondral bone morphology. Leptin-deficient (ob/ob) and leptin receptor-deficient (db/db) female mice compared
Lin Xu et al.
The Journal of clinical investigation, 118(1), 272-280 (2007-12-22)
Leptin is a hormone that reduces excitability in some hypothalamic neurons via leptin receptor activation of the JAK2 and PI3K intracellular signaling pathways. We hypothesized that leptin receptor activation in other neuronal subtypes would have anticonvulsant activity and that intranasal
Tamiris Lima Rachid et al.
Molecular and cellular endocrinology, 402, 86-94 (2015-01-13)
Browning is characterized by the formation of beige/brite fat depots in subcutaneous white adipose tissue (sWAT). This study aimed to examine whether the chronic activation of PPARalpha by fenofibrate could induce beige cell depots in the sWAT of diet-induced obese
Disruption of protein kinase A in mice enhances healthy aging.
Linda C Enns, John F Morton, Piper R Treuting, Mary J Emond, Norman S Wolf, G S McKnight et al.
Testing null
Prostate cancer cell proliferation and angiogenesis in different obese mice models.
Ribeiro AM, Andrade S, Pinho F, Monteiro JD, Costa M, Lopes C, Aguas AP, Monteiro MP
International Journal of Experimental Pathology null
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