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product name
Human FGF-23 ELISA Kit, This Human FGF-23 ELISA Kit is used to measure & quantify FGF-23 levels in Metabolism & Inflammation & Immunology research.
质量水平
种属反应性
human
包装
kit of 1 × 96 wells
参数
50 μL sample volume (4hr assay)
assay range
sensitivity: 9.9 pg/mL
(minimum detectable concentrations in tissue culture/serum/plasma)
standard curve range: 9.9-2400 pg/mL
inter-assay cv: <11%
intra-assay cv: <11%
技术
ELISA: suitable
输入
sample type cell culture supernatant
sample type serum
sample type plasma (K2 EDTA)
应用
research use
检测方法
colorimetric (450nm/590nm)
运输
wet ice
储存温度
2-8°C
一般描述
Studies demonstrate that Fibroblast Growth Hormone-23 plays a critical role as a phosphate-regulating hormone. FGF-23 is responsible for the inhibition of renal tubular reabsorption of inorganic phosphorus and, consequently, the regulation of phosphorus homeostasis. FGF-23 mRNA is expressed in the brain, in the thymus at low levels, in dendritic cells, with the highest expression in osteocytes and osteoblasts during phases of active bone remodeling. Because circulating levels of FGF-23 are regulated by vitamin D and phosphorus, normal skeletal and soft tissue development require vitamin D and a functional vitamin D signaling pathway. Diseases resulting from aberrant FGF-23 expression include inherited forms of rickets, certain kidney diseases and phosphorus-related tumors.
特异性
The antibody pair used in this assay cross-reacts 0.01% to Human FGF- 21 and 0.01% to FGF-19.
No significant cross-reactivity has been observed to other human and rat molecules/hormones tested
No significant cross-reactivity has been observed to other human and rat molecules/hormones tested
应用
50µl sample size, 2-Step assay with <4hr incubation time.
Research Category
Stem Cell Research
Stem Cell Research
Used to detect/quantify: FGF-23
其他说明
Please contact Technical Service for linearity of dilution.
免责声明
For research use only. Not for use in diagnostic procedures.
警示用语:
Danger
危险分类
Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Met. Corr. 1 - Skin Sens. 1
WGK
WGK 3
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