ECM642
体外血管通透性试验(96孔)
This In Vitro Vascular Permeability Assay kit employs a 96-well plate, and provides an efficient system for evaluating the effects of chemicals & drug compounds on endothelial cell adsorption, transport & permeability.
别名:
Endothelial cell model for permeability assay
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1 EA
CN¥7,908.02
About This Item
UNSPSC代码:
12352207
eCl@ss:
32161000
NACRES:
NA.32
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此商品 | P8375 | P8415 | P2088 |
|---|---|---|---|
| form essentially salt-free, lyophilized powder | form essentially salt-free, lyophilized powder | form essentially salt-free, lyophilized powder | form essentially salt-free, lyophilized powder |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| mol wt ~44 kDa | mol wt ~44 kDa | mol wt ~44 kDa | mol wt ~44 kDa |
| solubility 0.1 M phosphate buffer: soluble (pH 6.0), H2O: soluble | solubility 0.1 M phosphate buffer: soluble 10 mg/mL, clear, orange to red (pH 6.0) | solubility 0.1 M phosphate buffer: soluble (pH 6.0), H2O: soluble | solubility - |
| Quality Level 200 | Quality Level 300 | Quality Level 200 | Quality Level 300 |
应用
Millipore®体外血管通透性测定试剂盒为评估化学物质和药物化合物对内皮细胞吸附，转运和通透性的影响提供了有效的系统。它是测量可能破坏或保护内皮单层的化合物的理想选择。每个体外血管通透性测定试剂盒均包含足以评估96个样品的试剂。 体外血管通透性测定试剂盒预期仅用于研究用途，不用于诊断或治疗应用。
研究类别
细胞结构
细胞结构
组分
96孔渗透性插入组件，胶原涂层：一个96孔接收器托盘，包含96个预先涂有I型鼠尾胶原的连接的多孔细胞培养插件。
接收器托盘，96孔：两个96孔板。
FITC-葡聚糖溶液：两小瓶含有250 µL.
细胞染色液：一瓶含有10 mL
黑色平板，96孔不透明：一个96孔板。
接收器托盘，96孔：两个96孔板。
FITC-葡聚糖溶液：两小瓶含有250 µL.
细胞染色液：一瓶含有10 mL
黑色平板，96孔不透明：一个96孔板。
储存及稳定性
在2-8°C下储存试剂盒材料；自接收之日起4个月内使用。 请勿冷冻。
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Millipore is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的人类或动物食用或应用。
储存分类代码
10-13 - German Storage Class 10 to 13
WGK
WGK 2
You-Hong Cheng et al.
PloS one, 12(11), e0187949-e0187949 (2017-11-11)
Recent evidence suggests that chemokine CXCL12, the cognate agonist of chemokine receptors CXCR4 and ACKR3, reduces thrombin-mediated impairment of endothelial barrier function. A detailed characterization of the effects of CXCL12 on thrombin-mediated human lung endothelial hyperpermeability is lacking and structure-function
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Diabetic nephropathy is a leading cause of end-stage renal disease, characterized by endothelial dysfunction and a compromised glomerular permeability barrier. Dysregulation of the angiopoietin 1 (ANGPT1)/angiopoietin 2 (ANGPT2) signaling axis is implicated in disease progression. We recently described the discovery
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Environmental research, 180, 108900-108900 (2019-11-13)
Inhalation of welding fume (WF) can result in the deposition of toxic metals, such as manganese (Mn), in the brain and may cause neurological changes in exposed workers. Alterations in telomere length are indicative of cellular aging and, possibly, neurodegeneration.
Guo-Xiang Ruan et al.
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Herein, we report that vascular endothelial growth factor A (VEGF-A) engages the PI3K/Akt pathway by a previously unknown mechanism that involves three tyrosine kinases. Upon VEGF-A-dependent activation of VEGF receptor-2 (VEGFR-2), and subsequent TSAd-mediated activation of Src family kinases (SFKs)
Kibbeum Song et al.
European journal of pharmacology, 869, 172891-172891 (2019-12-27)
The blood-brain barrier (BBB) is a highly selective permeability barrier that separates the circulating blood from the brain and extracellular fluid in the central nervous system (CNS). The BBB is formed by cerebral endothelial cells connected by tight junctions. Prion
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在癌症研究、组织再生和血管生物学应用中通过以细胞为基础的血管生成检测来分析新血管的形成。
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