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CCYTOMAG-90K

Millipore

MILLIPLEX® 犬细胞因子/趋化因子磁珠板 - 免疫学多重分析

Simultaneously analyze multiple cytokine and chemokine biomarkers with Bead-Based Multiplex Assays using the Luminex technology, in mouse serum, plasma and cell culture samples.

别名:

canine interleukin immunoassay panel, luminex canine cytokine chemokine growth factor multiplex assay, luminex canine pro inflammatory anti inflammatory cytokine panel, millipore canine inflammation multiplex kit

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About This Item

UNSPSC代码:
12161503
eCl@ss:
32161000
NACRES:
NA.47

质量水平

种属反应性

canine

制造商/商品名称

Milliplex®

assay range

accuracy: 91-109%
sensitivity: 13.6 pg/mL
(IFN-γ)

sensitivity: 21.0 pg/mL
(MCP-1)

sensitivity: 21.7 pg/mL
(IL-8)

sensitivity: 3.2 pg/mL
(IP-10)

sensitivity: 3.5 pg/mL
(IL-2)

sensitivity: 3.7 pg/mL
(IL-6)

sensitivity: 5.3 pg/mL
(KC-like)

sensitivity: 5.8 pg/mL
(IL-18)

sensitivity: 6.1 pg/mL
(TNFα)

sensitivity: 7.5 pg/mL
(IL-7)

sensitivity: 8.5 pg/mL
(IL-10)

sensitivity: 9.0 pg/mL
(IL-15)

sensitivity: 9.2 pg/mL
(GM-CSF)

standard curve range: 12.2-50,000 pg/mL
(All analytes)

技术

multiplexing: suitable

检测方法

fluorometric (Luminex xMAP)

运输

wet ice

一般描述

除了研究用于狗营养和疾病研究的炎症外,犬类动物模型对于人类生物医学研究和药物研发也很重要。细胞因子和趋化因子是炎症和免疫中免疫细胞反应的分子介质。细胞因子和趋化因子的定量对于理解免疫系统以及研究疾病状态(例如自身免疫,过敏反应,脓毒症和癌症)至关重要。

MILLIPLEX®犬细胞因子面板是13重试剂盒,用于同时定量犬血清、血浆、组织/细胞裂解物和培养上清液样品中以下分析物的任何或全部:GM-CSF、IFNγ、KC样、IP-10、IL-2、IL-6、IL-7、IL-8, IL-10, IL-15、IL-18、MCP-1和TNF-α.该试剂盒采用96孔板,包含冻干标准混合物、两个内部检测质控品,可最多可测定38份样本,重复两次。

Luminex® xMAP®平台使用磁珠免疫分析格式,以实现理想的速度和灵敏度,同时定量多种分析物,从而显著提高生产力,同时节省宝贵的样本量。

面板类型:细胞因子/趋化因子

特异性

交叉反应性
抗体与该面板中任何其他分析物之间的交叉反应性都为无法检测或可忽略。
检测板内不同分析物之间不存在或可忽略的交叉反应性。

应用

  • 分析物:GM-CSF、IFNγ、IP-10、IL-2、IL-6、IL-7、IL-8、IL-10、IL-15、IL-18、KC样,MCP-1和TNF-α。
  • 推荐的样品类型:犬血清、血浆、细胞培养上清液和组织/细胞裂解物
  • 推荐的样品稀释度:25μL血浆或血清的1:3稀释液,或25 μL细胞培养上清液
  • 分析运行时间:4℃过夜或室温(20-25℃)下2小时
  • 研究类别:炎症 & 免疫学

特点和优势

通过在此面板中选择可用的分析物来设计多重试剂盒。

包装

单个试剂盒即可满足您的所有需求。

联系

替代:CCYTO-90K

储存及稳定性

试剂盒组分建议的存储温度为2-8°C。

其他说明

请联系技术服务部进行稀释度线性研究。

法律信息

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

警示用语:

Danger

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

靶器官

Respiratory Tract

储存分类代码

10 - Combustible liquids

法规信息

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Chad B Maki et al.
Frontiers in veterinary science, 7, 570-570 (2020-10-29)
This study was conducted to investigate the therapeutic effect of allogeneic adipose-derived MSCs on dogs with hip osteoarthritis (OA). Twenty dogs with bilateral osteoarthritis of the coxofemoral (hip) joint, diagnosed by a veterinarian through physical examination and radiographs were randomly
Bing Wang et al.
Acta biomaterialia, 116, 259-267 (2020-09-17)
In periodontal treatment, topical adjunctive therapy with antimicrobials or anti-inflammatory agents is frequently applied. However, currently available drug carrier biomaterials often exhibit poor perfusion into small crevices, such as the deep and irregular periodontal pockets, due to relatively high viscosity.
Gustavo Rodrigues Martins et al.
Mediators of inflammation, 2016, 9512743-9512743 (2016-03-19)
Inflammation results in the production of cytokines, such as interleukin- (IL-) 4 and IL-10 with immunosuppressive properties or IL-6 and TNF-α with procarcinogenic activity. Furthermore, NF-κB is the major link between inflammation and tumorigenesis. This study verified the interaction between
J L Tuohy et al.
Journal of veterinary internal medicine, 30(4), 1167-1178 (2016-06-25)
Monocytes/macrophages are likely key cells in immune modulation in dogs with osteosarcoma (OSA). Increased peripheral monocyte counts are negatively correlated with shorter disease-free intervals in dogs with OSA. Understanding the monocyte/macrophage's modulatory role in dogs with OSA can direct further
Julien R S Dandrieux et al.
Veterinary medicine and science, 5(2), 199-205 (2019-01-22)
A pharmacodynamic assay has been previously developed to monitor ciclosporin treatment in dogs by assessing inhibition of cytokine transcription after whole blood stimulation with 12-myristate 13-1 acetate and ionomycin (PMA/I). In this study, whole blood stimulation with either PMA/I or

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我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

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