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Merck
CN

CC065

Human Tenascin

from human glioma cell line (U251), liquid, 0.1 mg/mL, suitable for cell culture

别名:

TN-C, Tenascin, Hexabrachion, Cytotactin, Neuronectin

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关于此项目

UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.75

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产品名称

人Tenascin-C纯化蛋白,

biological source

human

assay

>97% (SDS-PAGE)

form

liquid

mol wt

280—300 kDa

manufacturer/tradename

Chemicon®

concentration

0.1 mg/mL

technique(s)

cell culture | mammalian: suitable

input

sample type induced pluripotent stem cell(s)
sample type mesenchymal stem cell(s)
sample type neural stem cell(s)
sample type pancreatic stem cell(s)
sample type: human embryonic stem cell(s)
sample type epithelial cells
sample type hematopoietic stem cell(s)

solubility

water: soluble

NCBI accession no.

NM_002160.2

UniProt accession no.

P24821

binding specificity

Peptide Source: Fibrinogen

shipped in

dry ice

storage temp.

−70°C

Quality Level

100

Gene Information

human ... TNC(3371)

相关类别

Application

细胞粘连分析。

最佳工作稀释度必须由最终用户进行确定。

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

General description

产品来源：人胶质瘤细胞系（U251）。
纯化的人腱生蛋白-C蛋白。已知肌腱蛋白可：1）在中枢神经紧张的系统和间充质来源器官的发育中起积极作用；2）存在于成人肿瘤的脉管系统中；和3）在细胞粘连中起作用。经SDS-PAGE分析，蛋白迁移在280-300kD左右。

Other Notes

替代：CC066

Physical form

纯化的蛋白以不含防腐剂的PBS液体形式提供。

Preparation Note

自收到之日起，在-70ºC可最多保存12个月。 应避免反复冻/融循环。

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

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Reza Mirzaei et al.
Oncoimmunology, 7(10), e1478647-e1478647 (2018-10-06)
The dismal prognosis of glioblastoma is attributed in part to the existence of stem-like brain tumor-initiating cells (BTICs) that are highly radio- and chemo-resistant. New approaches such as therapies that reprogram compromised immune cells against BTICs are needed. Effective immunotherapies
Cecelia C Yates et al.
Cell transplantation, 26(1), 103-113 (2016-07-28)
Mesenchymal stem cells (MSCs) remain of great interest in regenerative medicine because of their ability to home to sites of injury, differentiate into a variety of relevant lineages, and modulate inflammation and angiogenesis through paracrine activity. Many studies have found
Ting-Yu Huang et al.
BioMed research international, 2015, 712546-712546 (2015-04-04)
Urodele amphibians (Ambystoma mexicanum), unique among vertebrates, can regenerate appendages and other body parts entirely and functionally through a scar-free healing process. The wound epithelium covering the amputated or damaged site forms early and is essential for initiating the subsequent
Chimwemwe Mwase et al.
Cells, 11(2) (2022-01-22)
Aberrant remodeling of the asthmatic airway is not well understood but is thought to be attributable in part to mechanical compression of airway epithelial cells. Here, we examine compression-induced expression and secretion of the extracellular matrix protein tenascin C (TNC)
Jian Cao et al.
Cell reports, 6(5), 868-877 (2014-03-04)
Metastasis is a major clinical challenge for cancer treatment. Emerging evidence suggests that aberrant epigenetic modifications contribute significantly to tumor formation and progression. However, the drivers and roles of such epigenetic changes in tumor metastasis are still poorly understood. Using
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实验方案

ECM Coating Protocols for Millicell®

This page covers the ECM coating protocols developed for four types of ECMs on Millicell®-CM inserts, Collagen Type 1, Fibronectin, Laminin, and Matrigel.

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