Anti-CD34 Class III Antibody, clone 581

Clone 581 reacts with the class III CD34 epitope is resistant to neuraminidase, chymopapain and glycoprotease.

The antibody reacts with a single-chain 105-120 kDa heavily O-glycosylated transmembrane glycoprotein which is expressed on haematopoietic progenitor cells, vascular endothelium and some tissue fibroblasts. The intracellular chain of the CD34 antigen is a site of phosphorylation by activated protein kinase C suggesting a putative role in signal transduction. CD34 may also play a role in the adhesion of specific antigens to endothelium.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

Study of the Class III CD34 epitope by FACS

Optimal working dilutions must be determined by the end user.

This Anti-CD34 Antibody, Class III, clone 581 is validated for use in FC for the detection of CD34 Class III.

Format: Purified

Protein G affinity chromatography. The monoclonal is presented at a concentration of 100μg/1ml in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. We recommend that each laboratory determine an optimum working titre for use in its particular application.

For use within 1 month of purchase store at +4°C, for long term storage aliquot antibody into small volumes and store at -20°C.

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