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Merck
CN
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主要文件

CBL2117

Sigma-Aldrich

Anti-Interleukin-6 Antibody, clone B-E8

clone B-E8, Chemicon®, from mouse

别名:

IL-6, B-cell stimulatory factor 2, Interferon beta-2

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

mouse

质量水平

100
300

抗体形式

purified antibody

抗体产品类型

primary antibodies

克隆

B-E8, monoclonal

种属反应性

human

请勿与下列物质发生反应

mouse

制造商/商品名称

Chemicon®

技术

ELISA: suitable
flow cytometry: suitable
immunohistochemistry: suitable
neutralization: suitable

同位素/亚型

IgG1

NCBI登记号

UniProt登记号

运输

wet ice

基因信息

human ... IL6(3569)

特异性

Recognizes natural and recombinant forms of human Interleukin-6 with an affinity of 0.5 nM. Inhibits IL-6 binding to its receptors and blocks Interleukin-6 induced proliferation on B9 cells.

免疫原

Recombinant human IL-6.

应用

Blocks Interleukin-6 induced proliferation on B9 cells: 20pg of antibody neutralizes the activity of 1U of IL-6. It is recommended that the sodium azide is removed from the antibody prior to use in this application.

Immunohistochemistry on frozen sections

Optimal working dilutions must be determined by the end user.
Detect Interleukin-6 using this Anti-Interleukin-6 Antibody, clone B-E8 validated for use in ELISA, FC, IH, NEUT.
Research Category
Inflammation & Immunology
Research Sub Category
Cytokines & Cytokine Receptors

联系

Replaces: 04-1095

外形

Format: Purified
The monoclonal is purified from tissue culture supernatant by ion exchange chromatography and is presented as a liquid in phosphate buffered saline, pH 7.2.

储存及稳定性

Store at 2-8°C for up to 12 months from date of receipt. For long term storage aliquot antibody into small volumes and store at -20°C. Avoid repeated freeze-thaw cycles.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


分析证书(COA)

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Microglia derived IL-6 suppresses neurosphere generation from adult human retinal cell suspensions.
Balini Balasubramaniam,Debra A Carter,Eric J Mayer,Andrew D Dick
Experimental Eye Research null
Immunohistochemical detection of interleukin-6 in human skeletal muscle fibers following exercise.
Penkowa, M; Keller, C; Keller, P; Jauffred, S; Pedersen, BK
Faseb Journal null
Elevated levels of IL-18 in plasma and skeletal muscle in chronic obstructive pulmonary disease.
A M W Petersen,M Penkowa,M Iversen,L Frydelund-Larsen,J L Andersen,J Mortensen,P Lange,B K Pedersen
Lung null
Berberine inhibits inflammatory response and ameliorates insulin resistance in hepatocytes.
Tianjiong Lou,Zhongai Zhang,Zhilei Xi,Kang Liu,Lin Li,Baolin Liu,Fang Huang
Inflammation null
Fang Huang et al.
Biochimie, 94(5), 1143-1150 (2012-02-09)
Puerarin is an isoflavonoid isolated from the root of the plant Pueraria lobata and has been used as a prescribed drug in China for the treatment of cardiovascular diseases in the clinical practice. Puerarin possesses potential therapeutic activities for metabolic

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