推荐产品
生物来源
mouse
质量水平
抗体形式
purified antibody
抗体产品类型
primary antibodies
克隆
DP2.15, monoclonal
种属反应性
bovine, human, chicken, rat, mouse
制造商/商品名称
Chemicon®
技术
immunocytochemistry: suitable
immunofluorescence: suitable
western blot: suitable
同位素/亚型
IgG1
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... DSP(1832)
特异性
This antibody shows distinct punctate membrane staining of desmoplakins 1 (MW 250 kDa) and 2 (MW 215 kDa) in stratified epithelia and simple epithelia, including glands, urothelium, thymic reticular epithelium, hepatocytes, intercalated disks of myocardium and arachnoid cells of meninges.
免疫原
Bovine desmoplakin 1 & 2
应用
Anti-Desmoplakin 1& 2 Antibody, clone DP2.15 detects level of Desmoplakin 1& 2 & has been published & validated for use in IF, WB & IC.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Cytoskeleton
Cytoskeleton
Western blot
Immunohistochemistry: 1:10; Frozen tissue
Immunofluorescence
Optimal working dilutions must be determined by the end user.
Immunohistochemistry: 1:10; Frozen tissue
Immunofluorescence
Optimal working dilutions must be determined by the end user.
外形
Format: Purified
Lyophilized. Reconstitute in 1 mL distilled water (final solution contains 0.09% sodium
azide, 0.5% BSA in PBS buffer, pH 7.4
azide, 0.5% BSA in PBS buffer, pH 7.4
储存及稳定性
Reconstituted antibody can be stored at 2°-8°C for up to 12 months from date of receipt. Antibody can also be stored at -20°C in undiluted aliquots.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Andrew Muroyama et al.
eLife, 6 (2017-09-05)
The physiological functions of microtubules (MTs) are poorly understood in many differentiated cell types. We developed a genetic toolkit to study MT dynamics and function in diverse cells. Using TRE-EB1-GFP mice, we found that MT dynamics are strongly suppressed in
Annika Gross et al.
Cellular and molecular gastroenterology and hepatology, 13(4), 1181-1200 (2021-12-21)
Desmosomes are intercellular junctions connecting keratin intermediate filaments of neighboring cells. The cadherins desmoglein 2 (Dsg2) and desmocollin 2 mediate cell-cell adhesion, whereas desmoplakin (Dsp) provides the attachment of desmosomes to keratins. Although the importance of the desmosome-keratin network is
Emily I Bartle et al.
The Journal of cell biology, 219(6) (2020-05-14)
Desmosomes are cell-cell junctions that provide mechanical integrity to epithelial and cardiac tissues. Desmosomes have two distinct adhesive states, calcium-dependent and hyperadhesive, which balance tissue plasticity and strength. A highly ordered array of cadherins in the adhesive interface is hypothesized
Chi-Hsiao Yeh et al.
International journal of molecular sciences, 22(21) (2021-11-14)
Aging is the major risk factor for cardiovascular disease, which is the leading cause of mortality worldwide among aging populations. Cisd2 is a prolongevity gene that mediates lifespan in mammals. Previously, our investigations revealed that a persistently high level of
Wenxiu Ning et al.
Cell stem cell, 28(3), 436-452 (2020-12-03)
Basal stem cells fuel development, homeostasis, and regeneration of the epidermis. The proliferation and fate decisions of these cells are highly regulated by their microenvironment, including the basement membrane and underlying mesenchymal cells. Basal progenitors give rise to differentiated progeny
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