产品名称
抗整合素 αM [CD11b] 抗体，克隆OX-42, clone OX-42, Chemicon®, from mouse
isotype
IgG2a
biological source
mouse
conjugate
unconjugated
antibody form
purified antibody
antibody product type
primary antibodies
clone
OX-42, monoclonal
species reactivity
rat
packaging
antibody small pack of 25 μg
manufacturer/tradename
Chemicon®
technique(s)
flow cytometry: suitable
immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
immunoprecipitation (IP): suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
storage temp.
2-8°C
target post-translational modification
unmodified
Quality Level
Gene Information
rat ... Itgam(25021)
Analysis Note
对照
脑组织
脑组织
Application
使用经验证可用于FC、IH、IH（P）&IP的抗整合素αM CD11b抗体（克隆OX-42）检测整合素αM[CD11b]。
研究子类别
整合素
整合素
研究类别
细胞结构
细胞结构
Biochem/physiol Actions
可识别大多数巨噬细胞（包括常驻腹膜和活化巨噬细胞）、枯否细胞，但仅识别约35%的肺泡巨噬细胞。 该抗体还广泛标记大脑中的树突状细胞，粒细胞和具有小胶质细胞形态的细胞。该抗体沉淀150、103和95 kDa的三种多肽。该抗体可抑制补体介导的玫瑰花结，可能是IC3b的人类受体的大鼠等效物（称为CR3）。
融合伴侣：NSO骨髓瘤细胞系。
融合伴侣：NSO骨髓瘤细胞系。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
整联蛋白αM/β2与单核细胞、巨噬细胞和粒细胞的各种粘附性各种相互作用以及介导补体包被颗粒的摄取有关。它与第三补体成分iC3b片段的受体CR 3相同。它可能识别C3b中的R-G-D肽。整合素αM/β2也是纤维蛋白原，因子X和ICAM1的受体。可识别纤维蛋白原γ链的P1和P2肽。
Immunogen
大鼠腹腔巨噬细胞
Other Notes
浓度：请参考批次特异性浓缩物的检验报告。
Physical form
单克隆抗体存在于含有10mM叠氮化钠的磷酸盐缓冲液中。
形式：纯化
纯化的蛋白 A
Preparation Note
若购买后1个月内使用，则储存于+4°C，若要长期储存，则将抗体等分成小体积并储存于-20°C。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
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