物料
PVDF membrane
polyester screen
polypropylene housing (polypropylene silicone)
silicone O-ring
无菌性
non-sterile; γ-irradiated
储存条件
dry at room temperature
room temperature (15-30°C)
参数
7.37 L/min-m2 flow rate
技术
tangential flow filtration (TFF): suitable
直径 × 宽度 × 高度
33.0 cm (13.0 in) × 23.4 cm (9.2 in) × 37.6 cm (14.8 in)
过滤面积
3.8 m2
体积
3.5 L , Filter Only
3500 mL
4.1 L , Assembly
41000 mL
基质
Durapore®
孔径
5.0 μm
pH值（酸碱度）
4-8
应用
mAb
recombinant protein
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一般描述
The Cellicon® Filter Assembly is designed to meet your perfused seed train challenges. It is a flat sheet cell retention filter running in tangential flow filtration mode part of a single-use assembly. Perfusion operations deliver high-density cell cultures that alleviate the burden of processing large production bioreactor volumes while increasing manufacturing flexibility. Introducing perfusion to your seed train makes it possible to inoculate a higher quantity of cells for one or more production bioreactors, thus increasing process efficiency.
应用
Microfiltration and Seed Train Perfusion
特点和优势
- Predictable linear scalability from lab to manufacturing scale
- Reliable and reproducible performance
- Gentle on cells, maximizing cell density and viability
- Easy installation, with smooth connection to bioreactor through welding or sterile connectors
包装
The Cellicon® filter packaging meets the requirements of the American Society for Testing and Materials (ASTM) Integrity Test Procedure D4169. The Cellicon® filter and assembly are secured in foam parts which is then double bagged. A caution label and a gamma indicator label are included on the inner bag. The double bagged Cellicon® filter Assembly is individually boxed. A Certificate of Quality is available electronically.
其他说明
The Emprove® Program complements the product portfolio through comprehensive documentation to support qualification, risk assessment and process optimization needs.
Consolidation of product specific testing, quality and regulatory information to simplify compliance requirements.
Convenient 24/7 access to up-to-date product information.
Consolidation of product specific testing, quality and regulatory information to simplify compliance requirements.
Convenient 24/7 access to up-to-date product information.
法律信息
CELLICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Durapore is a registered trademark of Merck KGaA, Darmstadt, Germany
Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
法规信息
新产品
相关内容
Enhance perfused seed train efficiency with our cell retention solution. Real-time monitoring and control.
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