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安全信息

APOMAG-62K

Millipore

MILLIPLEX®人载脂蛋白磁珠板-心血管疾病多重测定

This Bead-Based Multiplex Assay, using the Luminex® xMAP® technology, enables the simultaneous analysis of Apo AI, Apo AII, Apo B, Apo CII, Apo CIII, Apo E.

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别名:
human apolipoprotein CVD immunoassay panel, luminex human apolipoprotein cardiovascular disease multiplex assay, millipore human apolipoprotein CVD multiplex kit
UNSPSC代码:
12161503
eCl@ss:
32161000
NACRES:
NA.84

特点

This Bead-Based Multiplex Assay, using the Luminex® xMAP® technology, enables the simultaneous analysis of Apo AI, Apo AII, Apo B, Apo CII, Apo CIII, Apo E.

质量水平

200

种属反应性

human

制造商/商品名称

Milliplex®

assay range

accuracy: 85%
(Apo E)
accuracy: 86%
(Apo AI)
accuracy: 89%
(Apo CIII)
accuracy: 92%
(Apo B)
sensitivity: 1.00 ng/mL
(Apo AII)
sensitivity: 1.22 ng/mL
(Apo CII)
sensitivity: 1.42 ng/mL
(Apo E)
sensitivity: 1.48 ng/mL
(Apo AI)
sensitivity: 1.71 ng/mL
(Apo CIII)
sensitivity: 4.84 ng/mL
(Apo B)

技术

multiplexing: suitable

检测方法

fluorometric (Luminex xMAP)

运输

wet ice

相关类别

一般描述

随着对越来越多的肥胖症、2型糖尿病和相关心血管疾病的病例进行描述和研究，代谢综合征越来越受到医学界的重视。

MILLIPLEX®人载脂蛋白检测板是一种6重试剂盒，用于同时定量血清、血浆、组织培养上清液或其他生物样品中以下分析物的任何或全部：APOA-1，APOA-2，APOB，APOC-2，APOC-3和APOE。该试剂盒采用96孔格式，包含冻干标准混合物、两个内部检测质控品，可最多可测定38份样品，重复两次。

Luminex® xMAP®平台使用磁珠免疫分析格式，以实现理想的速度和灵敏度，同时定量多种分析物，从而显著提高生产力，同时节省宝贵的样品量。

面板类型：心血管

特异性

交叉反应性
为了测试检测板中的测定方法之间的交叉反应性，以比校准曲线中最高浓度高4倍的浓度制备单个载脂蛋白标准品，并在6重分析中使用含有固定化捕获抗体和单个检测抗体的多重微珠进行测试。检测板内的交叉反应性可忽略不计。

应用

  • 分析物：Apo AI，Apo AII，Apo B，Apo CII，Apo CIII，Apo E
  • 推荐的样品类型：人血清，血浆，组织培养上清液或其他生物样品
  • 推荐的样品稀释度：10 μL 1：4,000稀释的血浆或血清
  • 分析运行时间：初次培养1小时，然后二次培养30分钟，均在室温（20-25℃）下进行。
  • 研究子类别：心血管疾病

特点和优势

通过在此面板中选择可用的分析物来设计多重试剂盒。

其他说明

标准曲线范围：有关详细信息，请参阅试剂盒方案。
请联系技术服务部进行稀释度线性研究。

法律信息

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

警示用语：

Danger

危险分类

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

靶器官

Respiratory Tract

储存分类代码

10 - Combustible liquids

WGK

WGK 3

法规信息

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Anna Posod et al.
Journal of the American Heart Association, 8(8), e011199-e011199 (2019-04-11)
Background Little is known about plasma apolipoprotein profiles in very preterm-born and term-born preschool children compared with the adult population. This is of particular interest because apolipoprotein composition might contribute to cardiometabolic outcome in later life. Methods and Results Children
Anastasiia S Boiko et al.
Heliyon, 5(7), e02033-e02033 (2019-07-19)
Schizophrenia is associated with a lowered life expectancy due to cardiovascular disease. This is, at least in part, related to an increased vulnerability to the development of metabolic syndrome (MetS) in patients with schizophrenia. The dysregulation of apolipoproteins (Apos) may
Elise Grytten et al.
Clinical nutrition (Edinburgh, Scotland), 40(5), 2556-2575 (2021-05-03)
Marine-derived omega-3 (n-3) polyunsaturated fatty acids (PUFAs), mainly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), lower circulating levels of triacylglycerols (TAGs), and the plant-derived omega-6 (n-6) PUFA linoleic acid (LA) may reduce cholesterol levels. Clinical studies on effects of these
Xiaoke Yin et al.
Circulation. Cardiovascular genetics, 10(6) (2017-12-15)
Mass spectrometry is selective and sensitive, permitting routine quantification of multiple plasma proteins. However, commonly used nanoflow liquid chromatography (LC) approaches hamper sample throughput, reproducibility, and robustness. For this reason, most publications using plasma proteomics to date are small in
Consumption of buckwheat modulates the post-prandial response of selected gastrointestinal satiety hormones in individuals with type 2 diabetes mellitus.
Stringer, DM; Taylor, CG; Appah, P; Blewett, H; Zahradka, P
Metabolism, Clinical and Experimental null
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