产品名称
抗-Claudin-5抗体, from rabbit, purified by affinity chromatography
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
rat, mouse, horse, human
species reactivity (predicted by homology)
equine (based on 100% sequence homology), ox (based on 100% sequence homology)
packaging
antibody small pack of 25 μg
technique(s)
immunohistochemistry: suitable (paraffin)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
ambient
storage temp.
2-8°C
target post-translational modification
unmodified
Quality Level
Gene Information
human ... CLDN5(7122)
Analysis Note
对照
人肺组织裂解液
人肺组织裂解液
已通过蛋白质印迹法在人肺组织裂解液中进行了评估。
蛋白质印迹分析：0.1 µg/mL的该抗体在10 µg人肺组织裂解液中检测到Claudin-5。
蛋白质印迹分析：0.1 µg/mL的该抗体在10 µg人肺组织裂解液中检测到Claudin-5。
Application
免疫组化分析：一个代表性批次产品以1：800的稀释度在前列腺组织中检测到Clausin-5。
抗Claudin-5抗体可检测Claudin-5水平 & 已出版&并经过验证可用于WB、IH(P)。
研究子类别
粘附力（CAMs）
粘附力（CAMs）
研究类别
细胞结构
细胞结构
Biochem/physiol Actions
该抗体可识别Claudin-5的胞质结构域。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
Claudin-5是一种在心肺面综合征（TMVCF）中缺失的跨膜蛋白，可能与内皮紧密连接有关。Claudin-5仅在内皮细胞的细胞边界中发现。肝损伤期间窦状内皮细胞中较低的claudin-5水平可能导致其功能障碍。肿瘤血管中claudin-5的水平可能是肝细胞癌预后的潜在标志物。Claudin-5功能的丧失与致癌作用有关。
观测值〜17 kDa。
由于磷酸化作用和糖基化作用，可以观察到〜17 kDa和62 kDa的分子量（Ishizaki, T., et al. (2003).Experimental Cell Research.290:275–288).
由于磷酸化作用和糖基化作用，可以观察到〜17 kDa和62 kDa的分子量（Ishizaki, T., et al. (2003).Experimental Cell Research.290:275–288).
Immunogen
与人Claudin-5细胞质结构域对应的KLH缀合线性肽。
表位：细胞质结构域
Other Notes
浓度：请参考批次特异性浓缩物的分析证书。
Physical form
亲和纯化
在含 0.1 M Tris-甘氨酸（pH 7.4），150 mM NaCl 和 0.05％ 叠氮化钠的缓冲液中的纯化的兔多克隆抗体。
Preparation Note
自发运之日起，在 2-8°C 条件下可稳定保存1年
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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