生物来源
rabbit
质量水平
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
纯化方式
affinity chromatography
种属反应性
human, mouse
技术
immunohistochemistry: suitable (paraffin)
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... PCDH19(57526)
一般描述
Protocadherin-19, also known as Potential calcium-dependent cell-adhesion protein (PCDH19), is a single-pass type I membrane protein that is moderately expressed in all regions of the brain and ovary, and has low expression in other tissues. Defects in PCDH19 cause epileptic encephalopathy, early infantile type 9 (EIEE9), also known as epilepsy female-restricted with mental retardation.
免疫原
Epitope: Cytoplasmic domain
KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Protocadherin 19.
应用
Detect Protocadherin 19 using this Anti-Protocadherin 19 Antibody validated for use in IHC (Paraffin).
Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected Protocadherin 19 in mouse hypothalamus and hind brain tissues, whereas a 1:2,000 dilution from a representative lot detected Protocadherin 19 in human cerebellum tissue.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Adhesion (CAMs)
Adhesion (CAMs)
质量
Evaluated by Immunohistochemistry in human cerebral cortex tissue.
Immunohistochemistry Analysis: A 1:500 dilution of this antibody detected Protocadherin 19 in human cerebral cortex tissue.
Immunohistochemistry Analysis: A 1:500 dilution of this antibody detected Protocadherin 19 in human cerebral cortex tissue.
目标描述
126 kDa calculated
外形
Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Nature communications, 10(1), 3946-3946 (2019-09-04)
Cerebral cortex expansion is a hallmark of mammalian brain evolution; yet, how increased neurogenesis is coordinated with structural and functional development remains largely unclear. The T-box protein TBR2/EOMES is preferentially enriched in intermediate progenitors and supports cortical neurogenesis expansion. Here
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