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Merck
CN
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主要文件

ABT318

Sigma-Aldrich

Anti-Protocadherin 19 Antibody

from rabbit, purified by affinity chromatography

别名:

Protocadherin-19

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

rabbit

质量水平

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

纯化方式

affinity chromatography

种属反应性

human, mouse

技术

immunohistochemistry: suitable (paraffin)

NCBI登记号

UniProt登记号

运输

wet ice

靶向翻译后修饰

unmodified

基因信息

human ... PCDH19(57526)

一般描述

Protocadherin-19, also known as Potential calcium-dependent cell-adhesion protein (PCDH19), is a single-pass type I membrane protein that is moderately expressed in all regions of the brain and ovary, and has low expression in other tissues. Defects in PCDH19 cause epileptic encephalopathy, early infantile type 9 (EIEE9), also known as epilepsy female-restricted with mental retardation.

免疫原

Epitope: Cytoplasmic domain
KLH-conjugated linear peptide corresponding to the cytoplasmic domain of human Protocadherin 19.

应用

Detect Protocadherin 19 using this Anti-Protocadherin 19 Antibody validated for use in IHC (Paraffin).
Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected Protocadherin 19 in mouse hypothalamus and hind brain tissues, whereas a 1:2,000 dilution from a representative lot detected Protocadherin 19 in human cerebellum tissue.
Research Category
Cell Structure
Research Sub Category
Adhesion (CAMs)

质量

Evaluated by Immunohistochemistry in human cerebral cortex tissue.

Immunohistochemistry Analysis: A 1:500 dilution of this antibody detected Protocadherin 19 in human cerebral cortex tissue.

目标描述

126 kDa calculated

外形

Affinity purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Xiaohui Lv et al.
Nature communications, 10(1), 3946-3946 (2019-09-04)
Cerebral cortex expansion is a hallmark of mammalian brain evolution; yet, how increased neurogenesis is coordinated with structural and functional development remains largely unclear. The T-box protein TBR2/EOMES is preferentially enriched in intermediate progenitors and supports cortical neurogenesis expansion. Here

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