生物来源
rabbit
质量水平
抗体形式
serum
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
human, mouse, rat
种属反应性（根据同源性预测）
all
技术
western blot: suitable
同位素/亚型
IgG
运输
wet ice
靶向翻译后修饰
unmodified
一般描述
蛋白质亚磺酸的形成是可逆的翻译后修饰，可用于监测目标蛋白质内反应性半胱氨酸上的蛋白质氧化。这可以用二甲酮衍生的蛋白质亚磺酸检测到。
特异性
该抗体识别亚磺酸修饰的蛋白质。针对所有物种的泛修饰。
免疫原
对应于次磺酸修饰蛋白的线性肽。
应用
免疫荧光分析： 先前批次已被独立实验室用于IF。(Seo, YH, et al. (2009).PNAS.106(38): 16163-16168.)
抗-磺酸修饰半胱氨酸（2-Thiodimedone-Specific Ig）抗体可检测磺酸修饰半胱氨酸水平，&经发表 & 验证可用于 WB。
质量
已通过蛋白质印迹法在大鼠心室肌细胞裂解液中进行了评估。
蛋白质印迹分析：该抗体（稀释度 01:1,000 ）在 10 µg 大鼠心室肌细胞裂解物中检测到亚磺酸修饰的蛋白。
蛋白质印迹分析：该抗体（稀释度 01:1,000 ）在 10 µg 大鼠心室肌细胞裂解物中检测到亚磺酸修饰的蛋白。
目标描述
预计会有泛抗体涂片。
Not finding the right product?
Try our 产品选型工具.
WGK
WGK 1
Ester Zito et al.
Molecular cell, 48(1), 39-51 (2012-09-18)
Endoplasmic reticulum (ER) thiol oxidases initiate a disulfide relay to oxidatively fold secreted proteins. We found that combined loss-of-function mutations in genes encoding the ER thiol oxidases ERO1α, ERO1β, and PRDX4 compromised the extracellular matrix in mice and interfered with
Nannan Zhou et al.
The Journal of clinical investigation, 133(24) (2023-12-15)
Elevation of reactive oxygen species (ROS) levels is a general consequence of tumor cells' response to treatment and may cause tumor cell death. Mechanisms by which tumor cells clear fatal ROS, thereby rescuing redox balance and entering a chemoresistant state
Phillip A Wages
Current protocols in toxicology, 71, 17-17 (2017-02-02)
Protein sulfenylation is a post-translational modification that is linked to many cell signaling networks and specific protein functions, thus the detection of any sulfenylated protein after a toxicological exposure is of importance. Specifically, the detection of protein sulfenylation can provide
Nikki L Jernigan et al.
PloS one, 12(6), e0180455-e0180455 (2017-07-01)
Pulmonary arterial hypertension is associated with a decreased antioxidant capacity. However, neither the contribution of reactive oxygen species to pulmonary vasoconstrictor sensitivity, nor the therapeutic efficacy of antioxidant strategies in this setting are known. We hypothesized that reactive oxygen species
Juliana Navarro-Yepes et al.
Molecular neurobiology, 53(8), 5229-5251 (2015-09-28)
Intracytoplasmic inclusions of protein aggregates in dopaminergic cells (Lewy bodies) are the pathological hallmark of Parkinson's disease (PD). Ubiquitin (Ub), alpha (α)-synuclein, p62/sequestosome 1, and oxidized proteins are the major components of Lewy bodies. However, the mechanisms involved in the
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系技术服务部门