Anti-Neutral amino acid transporter (ASCT2) Antibody

Neutral amino acid transporter, also known as ASCT2, is an alternate of the ASC (alanine-, serine-, cysteine-) transport system and is highly expressed in rat astroglia-rich cultures while not highly expressed in rat neuron-rich cultures. ASCT2 is also thought to be important in the glutamine release from cells. ASCT2 has been implicated in the growth and survival of cancer cells, therefore making it a possible target for cancer therapy. ASCT2 is thought to be a crucial neuronal neutral amino acid transporter.

No homology found to mouse or rat. Other homologies: rhesus monkey (93% sequence homology).

This antibody recognizes Neutral amino acid transporter at the N-terminus.

Epitope: N-terminus

KLH-conjugated linear peptide corresponding to the N-terminus of Neutral amino acid transporter.

Anti-Neutral amino acid transporter (ASCT2) Antibody detects level of Neutral amino acid transporter (ASCT2) & has been published & validated for use in WB, IH(P).

Immunohistochemistry Analysis: 1:1000 dilution from a previous lot detected Neutral amino acid transporter in human prostate tissue.

Research Category
Neuroscience

Research Sub Category
Ion Channels & Transporters

Evaluated by Western Blot in human placenta tissue lysate.

Western Blot Analysis: 0.5 µg/mL of this antibody detected Neutral amino acid transporter on 10 µg of human placenta tissue lysate.

~ 57 kDa observed

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Control
Human placenta tissue lysate

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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