Anti-SELK Antibody

Selenoprotein K (SELK) is a selenoprotein that is localized at the endoplasmic reticulum, and highly expressed in the heart. SELK functions as an antioxidant that can bind to proteins such as the ER-associated degradation (ERAD) components p97 ATPase, Derlin-1 and -2, and SelS as well as proteins in the oligosaccharyltransferase complex. SELK may be involved in the Derlin-dependent ERAD of glycosylated misfolded proteins, is thought to be important in Ca2+ flux in immune cells, and is cleaved by m-calpain in resting macrophages.

KLH-conjugated linear peptide corresponding to human SELK.

Anti-SELK Antibody is a highly specific rabbit polyclonal antibody, that targets Selenoprotein K & has been tested in western blotting.

Research Category
Neuroscience

Research Sub Category
Developmental Neuroscience

Evaluated by Western Blotting in A20 cell lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected SELK in 15 µg of A20 cell lysate.

~10 kDa observed. Uncharacterized bands may appear in some lysate(s).

Antigen Affinity Purified

Purified rabbit polyclonal PBS with up to 0.1% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Control
A20 cell lysate

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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