推荐产品
生物来源
rabbit
质量水平
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
纯化方式
affinity chromatography
种属反应性
human
技术
immunocytochemistry: suitable
immunofluorescence: suitable
western blot: suitable
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... OTUD4(54726)
一般描述
OTU domain-containing protein 4 (OTUD4) is a member of the OTU (ovarian tumor) domain containing cysteine protease superfamily, in which the OTU domain generally confers deubiquitinase activity. High levels of OTUD4 are found in lung, ovary, testis, liver, heart skeletal muscle, kidney, and brain, with lower levels present in pancreas and spleen. Four isoforms of OTUD4 are known to exist, the shortest one being expressed specifically in HIV-1-infected cells.
免疫原
KLH-conjugated linear peptide corresponding to human OTUD4.
应用
Detect OTU domain-containing protein 4 using this rabbit polyclonal antibody, Anti-OTUD4 Antibody validated for use in western blotting, ICC & Immunofluorescence.
Immunocytochemistry Analysis: 2.5 µg/mL from a representative lot detected OTUD4 in Daudi cells.
Immunofluorescence Analysis: 20 µg/mL from a representative lot detected OTUD4 in Daudi cells.
Immunofluorescence Analysis: 20 µg/mL from a representative lot detected OTUD4 in Daudi cells.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Developmental Neuroscience
Developmental Neuroscience
质量
Evaluated by Western Blotting in Daudi cell lysate.
Western Blotting Analysis: 0.25 µg/mL of this antibody detected OTUD4 in 15 µg of Daudi cell lysate.
Western Blotting Analysis: 0.25 µg/mL of this antibody detected OTUD4 in 15 µg of Daudi cell lysate.
目标描述
~108 kDa observed. Uniprot describes four isoforms at ~17 kDa, ~24 kDa, ~117 kDa, and ~124 kDa Uncharacterized bands may appear in some lysates.
外形
Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.
储存及稳定性
Stable for 1 year at 2-8°C from date of receipt.
分析说明
Control
Daudi cell lysate
Daudi cell lysate
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Zhiqiang Wu et al.
Cancer cell international, 19, 99-99 (2019-04-24)
Radiotherapy is becoming one major therapeutics for non-small cell lung cancer (NSCLC). Identifying novel radiosensitizers will greatly increase the efficacy of radiotherapy and benefit more patients. OTU deubiquitinase 4 (OTUD4) has been reported involved in DNA damage repair pathways and
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