Anti-DDAH2 Antibody

Dimethylarginine dimethylaminohydrolase 2 (DDAH2) is also called N(G),N(G)-dimethylarginine dimethylaminohydrolase 2 (DDAH-2), DDAHII, Dimethylargininase-2, Protein G6a and S-phase protein. DDAH2 is involved in nitric oxide generation through the hydrolyzation of N(G),N(G)-dimethyl-L-arginine (ADMA) and N(G)-monomethyl-L-arginine (MMA) which are NOS inhibitors. DDAH2 is expressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of human DDAH2.

Detect Dimethylarginine dimethylaminohydrolase 2 using this rabbit polyclonal antibody, Anti-DDAH2 Antibody validated for use in western blotting & IHC (Paraffin).

Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected DDAH2 in human kidney and human cardiac myocytes tissue.

Research Category
Neuroscience

Research Sub Category
Developmental Signaling

Evaluated by Western Blotting in human heart tissue lysate.

Western Blotting Analysis: A 1:500 dilution of this antibody detected DDAH2 in 10 µg of human heart tissue lysate.

~36 kDa observed. Uncharacterized band(s) may appear in some lysates.

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

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