ABN278
抗Prospero同源盒蛋白1/PROX1抗体
from rabbit, purified by affinity chromatography
别名:
Prospero homeobox protein 1, Homeobox prospero-like protein PROX1, PROX-1
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
immunohistochemistry
western blot
western blot
Species reactivity:
mouse, rat
Citations:
9
Technique(s):
immunohistochemistry: suitable
western blot: suitable
western blot: suitable
Uniprot accession no.:
产品名称
抗Prospero同源盒蛋白1/PROX1抗体, from rabbit, purified by affinity chromatography
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
mouse, rat
species reactivity (predicted by homology)
bovine (based on 100% sequence homology), fish (based on 100% sequence homology), chicken (based on 100% sequence homology), human (based on 100% sequence homology)
technique(s)
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
mouse ... Prox1(19130)
Analysis Note
通过蛋白质印迹在HEK293核提取物中进行了评估。
蛋白质印迹分析：该抗体的1：500稀释液在10 µg HEK293核提取物中检测到Prospero同源盒蛋白1/Prox1。
蛋白质印迹分析：该抗体的1：500稀释液在10 µg HEK293核提取物中检测到Prospero同源盒蛋白1/Prox1。
Application
免疫组化分析：代表性批次的1：2,000的稀释液在小鼠E16胚胎丘脑组织中检测到Prospero同源盒蛋白1/PROX1（Prof. Samual Pleasure, University of California, San Francisco.）。
Alexa Fluor™是Life Technologies，Inc.的注册商标。
Alexa Fluor™是Life Technologies，Inc.的注册商标。
该抗Prospero同源盒蛋白1/PROX1抗体经验证可用于蛋白质印迹&IHC检测Prospero同源盒蛋白1/PROX1。
General description
PROX1（Prospero同源盒蛋白1）是果蝇Prospero的同源物，是一种含有同源盒的转录因子，可结合并充当肝受体同源物1（LRH1/NR5A2）的共受体。它是淋巴内皮细胞以及成肝细胞和肝细胞的特异性标志物。人Prox1与小鼠和大鼠Prox1具有97%的氨基酸序列一致性。
观察值〜95 kDa。Uniprot描述了83kDa的分子量，然而，由于SUMO化和/或替代起始位点，可在80-110kDa之间观察到该蛋白（Pan，M.R.，et al.（2009）.J Cell Sci. 122(Pt18):3358-3361.; Azuma, K., et al. (2011).Genes Cells.16(11):1063-1070.)。
Immunogen
KLH偶联的线性肽，对应于人Prospero同源盒蛋白1/PROX1的C末端。
Other Notes
替代品：AB5475
Legal Information
ALEXA FLUOR is a trademark of Life Technologies
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Charlotte M Ermine et al.
Journal of neuroscience research, 99(12), 3222-3237 (2021-10-16)
Animal modeling has played an important role in our understanding of the pathobiology of stroke. The vast majority of this research has focused on the acute phase following severe forms of stroke that result in clear behavioral deficits. Human stroke
Hidenori Ito et al.
Hippocampus, 29(7), 569-578 (2018-11-06)
The hippocampus is generally considered as a brain center for learning and memory. We have recently established an electroporation-mediated gene transfer method to investigate the development of neonatal dentate granule cells in vivo. Using this new technique, we introduced knockdown
Charlotte M Ermine et al.
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Key pathological features of Parkinson's Disease (PD) include the progressive degeneration of midbrain dopaminergic (DA) neurons and hindbrain noradrenergic (NA) neurons. The loss of DA neurons has been extensively studied and is the main cause of motor dysfunction. Importantly, however
Lu M Yang et al.
PLoS genetics, 15(7), e1008254-e1008254 (2019-07-06)
The mouse organ of Corti, housed inside the cochlea, contains hair cells and supporting cells that transduce sound into electrical signals. These cells develop in two main steps: progenitor specification followed by differentiation. Fibroblast Growth Factor (FGF) signaling is important
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