推荐产品
生物来源
rabbit
质量水平
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
纯化方式
affinity chromatography
种属反应性
mouse, rat
种属反应性(根据同源性预测)
bovine (based on 100% sequence homology), fish (based on 100% sequence homology), chicken (based on 100% sequence homology), human (based on 100% sequence homology)
技术
immunohistochemistry: suitable
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
mouse ... Prox1(19130)
一般描述
PROX1(Prospero同源盒蛋白1)是果蝇Prospero的同源物,是一种含有同源盒的转录因子,可结合并充当肝受体同源物1(LRH1/NR5A2)的共受体。它是淋巴内皮细胞以及成肝细胞和肝细胞的特异性标志物。人Prox1与小鼠和大鼠Prox1具有97%的氨基酸序列一致性。
免疫原
KLH偶联的线性肽,对应于人Prospero同源盒蛋白1/PROX1的C末端。
应用
免疫组化分析:代表性批次的1:2,000的稀释液在小鼠E16胚胎丘脑组织中检测到Prospero同源盒蛋白1/PROX1(Prof. Samual Pleasure, University of California, San Francisco.)。
Alexa Fluor™是Life Technologies,Inc.的注册商标。
Alexa Fluor™是Life Technologies,Inc.的注册商标。
该抗Prospero同源盒蛋白1/PROX1抗体经验证可用于蛋白质印迹&IHC检测Prospero同源盒蛋白1/PROX1。
质量
通过蛋白质印迹在HEK293核提取物中进行了评估。
蛋白质印迹分析:该抗体的1:500稀释液在10 µg HEK293核提取物中检测到Prospero同源盒蛋白1/Prox1。
蛋白质印迹分析:该抗体的1:500稀释液在10 µg HEK293核提取物中检测到Prospero同源盒蛋白1/Prox1。
目标描述
观察值〜95 kDa。Uniprot描述了83kDa的分子量,然而,由于SUMO化和/或替代起始位点,可在80-110kDa之间观察到该蛋白(Pan,M.R.,et al.(2009).J Cell Sci. 122(Pt18):3358-3361.; Azuma, K., et al. (2011).Genes Cells.16(11):1063-1070.)。
联系
替代品:AB5475
法律信息
ALEXA FLUOR is a trademark of Life Technologies
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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