Anti-CYP24A1 Antibody

Also known as Vitamin D(3) 24-hydroxylase, CYP24A1 is a member of the cytochrome P450 (CYP) family of enzymes. Most members of the CYP family can metabolize multiple substrates, and can catalyze multiple reactions. The CYP24A1 is a mitochondrial protein that starts the breakdown of 1,25-dihydrozyvitamin D3 by hydroxylation of the side chain to form calcitroic acid. This enzyme also has a role in calcium homeostasis and the vitamin D endocrine system.

Other Homologies: Bovine (92% sequence homology) and Rat (75% sequence homology).

KLH-conjugated linear peptide corresponding to human CYP24A1.

Anti-CYP24A1 Antibody is an antibody against CYP24A1 for use in 0.

Research Category
Neuroscience

Research Sub Category
Developmental Signaling

Evaluated by Western Blot in A549 cell lysate.

Western Blot Analysis: 0.2 µg/mL of this antibody detected CYP24A1 in 10 µg of A549 cell lysate.

~60 kDa observed. Two isoforms are known to exist at 59 kDa and 51 kDa This antibody is expected to recognize both isoforms.

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Control
A549 cell lysate

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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