Anti-RanBP2 Antibody

RAN-binding protein 2 (RanBP2), also known as Nucleoporin Nup358 (Nup358), is encoded by the RANBP2 gene. RanBP2/Nup358 regulates functions of multiple cellular proteins through direct interactions via distinct domains. RanBP2/Nup358 binding partners include Ran GTPase, importin-beta, exportin-1/CRM1, red opsin, subunits of the proteasome, cox11, the kinesin-1 isoforms KIF5B and KIF5C, and E2 enzyme UBC9, where it functions as an E3 SUMO-protein ligase and facilitates subsequent SUMOylation of protein substrates such as RanGAP and SP100.

Epitope: Internal repeat IR1+2 domain (IR)

Recombinant protein corresponding to the internal repeat IR1+2 domain (IR) of human RanBP2.

Anti-RanBP2 Antibody is an antibody against RanBP2 Antibody for use in Immunohistochemistry, Immunofluorescence.

Immunofluorescence Analysis: A 1:50 dilution from a representative lot detected RanBP2 in mouse retina cells (Paulo Ferreira, Duke University)
Immunofluorescence Analysis: A representative lot detected in mouse retina of RanBP2 transgenic mice (Cho, K., et al. (2014). JBC. 1-31).

Research Category
Neuroscience

Research Sub Category
Developmental Signaling

Evaluated by Immunohistochemistry in human retina tissue.

Immunohistochemistry Analysis: A 1:50 dilution of this antibody detected RanBP2 in human retina tissue.

358.2 kDa calculated

Affinity purified

Purified rabbit polyclonal in buffer containing PBS with 0.05% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Concentration: Please refer to lot specific datasheet.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.