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Merck
CN

ABE68

抗-FoxP1抗体

serum, from rabbit

别名:

forkhead box P1, fork head-related protein like B, glutamine-rich factor 1

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
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产品名称

抗-FoxP1抗体, serum, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human, mouse

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... FOXP1(27086)

Analysis Note

对照
RAW264.7细胞裂解物
通过蛋白质印迹对RAW264.7细胞裂解液进行了评估。

蛋白质印迹分析:该抗体的1:1,000的稀释液在10 µg RAW264.7细胞裂解物中检测到FoxP1。

Application

使用在ICC、WB、IHC中验证的抗FoxP1抗体(兔多克隆抗体)检测FoxP1(也称为叉头盒P1)、叉头相关蛋白(如B)、富含谷氨酰胺的因子1。
免疫细胞化学分析: 代表性批次的1:500稀释液在HeLa和NIH/3T3细胞中检测FoxP1。

免疫组化分析: 代表性批次已被独立实验室用于IH。(Lu, M.M., et al. (2002).Mechanisms of Development 119S:S197–S202.)
研究子类别
转录因子

发育信号
研究类别
表观遗传学 & 核功能

表观遗传学 & 核功能

Biochem/physiol Actions

该抗体可识别FoxP1。

Disclaimer

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

General description

叉头盒P1(FoxP1)是FOX转录因子家族的成员。已知该蛋白与家族成员FoxP2和FoxP4形成同二聚体和异二聚体。叉头盒家族具有广泛的功能。这些蛋白在免疫反应、器官发育和癌症的发展中起着重要作用。 FoxP1蛋白被广泛表达,并包含叉头(有翼螺旋)和C2H2锌指核酸结合基序。已经报告了由mRNA转录物的选择性剪接产生的至少四种不同的亚型。
观察值79 kDa。 选择性剪接可导致细胞类型依赖性亚型。

Immunogen

GST标记的重组蛋白,对应于小鼠FoxP1。
表位:未知

Other Notes

浓度:请参考批次特异性浓缩物的分析证书。

Physical form

含0.05%叠氮化钠的未纯化兔多克隆血清。
未纯化

Preparation Note

自收到之日起在-20°C可稳定保存1年。
使用建议:收到后,在取下瓶盖之前,将小瓶离心并轻轻混合溶液。分装到微量离心管中,并储存于 -20°C。避免反复冻融循环,以免损坏 IgG 和影响产品性能。

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存储类别

10 - Combustible liquids

wgk

WGK 1


分析证书(COA)

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Regulatory T cells (Treg cells), whose differentiation and function are controlled by transcription factor Foxp3, express the closely related family member Foxp1. Here we explored Foxp1 function in Treg cells. We found that a large number of Foxp3-bound genomic sites
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