Anti-THRAP3 Antibody

Thyroid hormone receptor-associated protein 3 (THRAP3) is also called Thyroid hormone receptor-associated protein complex 150 kDa component (Trap150). THRAP3 plays a role in pre-mRNA splicing and is possibly involved in nuclear mRNA decay. THRAP3 regulates signal-induced alternative splicing, cyclin-D1/CCND1 mRNA stability and response to DNA damage. THRP3 is ubiquitously expressed across tissues.

Recombinant protein corresponding to human THRAP3.

Detect Thyroid hormone receptor-associated protein 3 using this rabbit polyclonal antibody, Anti-THRAP3 Antibody validated for use in IP, ICC & western blotting.

Immunoprecipitation Analysis: A representative lot immunoprecipitated THRAP3 in U20S cell lysates (Beli, P., et al. (2012). Mol Cell. 46(2):212-215).
Immunocytochemistry Analysis: A representative lot detected THRAP3 in U20S cells (Bracken, C. P., et al. (2008). Cancer Res. 68(18):7621-7628).
Western Blotting Analysis: A representative lot detected THRAP3 in untreated, and etoposide treated, hydroxyurea treated, 4NQO treated, and irradiated U20S cell lysates (Beli, P., et al. (2012). Mol Cell. 46(2):212-215).
Western Blotting Analysis: A representative lot detected THRAP3 in U20S and THRAP3 transfected HEK293 cell lysates (Bracken, C. P., et al. (2008). Cancer Res. 68(18):7621-7628.).

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Chromatin Biology

Evaluated by Western Blotting in U2OS cell lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected THRAP3 in 10 µg of U2OS cell lysate.

~150 kDa observed

Protein A/G

Format: Purified

Purified rabbit polyclonal in buffer containing PBS with 0.05% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Control
U2OS cell lysate

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.