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ABE483

Sigma-Aldrich

抗-TFAM 抗体

serum, from rabbit

别名:

Transcription factor A, mitochondrial, mtTFA, Testis-specific high mobility group protein, TS-HMG

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

rabbit

质量水平

抗体形式

serum

抗体产品类型

primary antibodies

克隆

polyclonal

种属反应性

human, mouse, rat

技术

immunoprecipitation (IP): suitable
western blot: suitable

NCBI登记号

UniProt登记号

运输

wet ice

靶向翻译后修饰

unmodified

基因信息

human ... TFAM(7019)
mouse ... Tfam(21780)

一般描述

TFAM(也称mtTFA)是一种线粒体转录因子,它是线粒体转录的关键激活剂,也参与线粒体基因组复制。小鼠研究表明线粒体基因组拷贝数的调节和胚胎发育都需要该基因产物。

免疫原

His标记的重组蛋白,对应于小鼠mtTFA。

应用

使用经验证可用于蛋白质印迹&IP的该兔多克隆抗-TFAM抗体检测TFAM。
免疫沉淀分析:一个来自独立实验室的代表性批次使C2C12细胞裂解液做工的Chd2免疫沉淀(Harada,A.,et al.(2012).
研究子类别
转录因子
研究类别
表观遗传学&核功能

质量

通过蛋白质印迹法在C2C12 细胞裂解物中进行评价。

蛋白质印迹分析:该抗体的1:1,000 稀释液在10 µg C2C12细胞裂解液中检测到TFAM。

目标描述

观测值〜27 kDa

外形

兔多克隆抗血清,含0.05%叠氮化钠。
未纯化

储存及稳定性

自收到之日起在-20°C可稳定保存1年。
使用建议:收货后,在取下瓶盖之前,将小瓶离心并轻轻混合溶液。分装到微量离心管中,并储存于-20°C。避免反复冻融循环,以免损坏IgG和影响产品性能。

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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