ABE211
Anti-CFP1 Antibody
serum, from rabbit
别名:
CXXC finger 1 (PHD domain), PHD finger and CXXC domain-containing protein 1, CXXC-type zinc finger protein 1, cpG-binding protein, CpG binding protein, zinc finger, CpG binding-type containing 1, DNA-binding protein with PHD finger and CXXC domain
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About This Item
生物来源
rabbit
抗体形式
serum
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
human, rat
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... CXXC1(30827)
一般描述
CXXC finger protein 1 (CFP1) is part of the Setd1A and Setd1B methyltransferase compounds. Research shows that CFP1 also interacts with the cytosine methylation mechanism. CFP1 is necessary for development of mammals and is a key regulator of chromatin structure. Embryonic stem cells that are missing CFP1 are more susceptible to DNA-damaging agents and tend to build up more DNA damage. CFP1 has been shown to also be a regulator of DNA repair.
免疫原
GST-tagged recombinant protein corresponding to human CFP1.
应用
Use Anti-CFP1 Antibody (Rabbit Polyclonal Antibody) validated in WB to detect CFP1 also known as CXXC finger 1 (PHD domain), cpG-binding protein.
质量
Evaluated by Western Blot in HeLa nuclear extract.
Western Blot Analysis: 1:1,000 dilution of this antibody detected CFP1 on 10 µg of HeLa nuclear extract.
Western Blot Analysis: 1:1,000 dilution of this antibody detected CFP1 on 10 µg of HeLa nuclear extract.
目标描述
~78 kDa observed. A cross-reacting band observed at ~110 kDa
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
eLife, 10 (2021-10-21)
Transposable elements (TEs) are mobile genetic elements that make up a large fraction of mammalian genomes. While select TEs have been co-opted in host genomes to have function, the majority of these elements are epigenetically silenced by DNA methylation in
Chromosoma, 126(6), 681-695 (2017-05-21)
PR domain-containing protein 9 (PRDM9) is a major regulator of the localization of meiotic recombination hotspots in the human and mouse genomes. This role involves its DNA-binding domain, which is composed of a tandem array of zinc fingers, and PRDM9-dependent
eLife, 4, e06283-e06283 (2015-06-13)
MAF1 represses Pol III-mediated transcription by interfering with TFIIIB and Pol III. Herein, we found that MAF1 knockdown induced CDKN1A transcription and chromatin looping concurrently with Pol III recruitment. Simultaneous knockdown of MAF1 with Pol III or BRF1 (subunit of
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