Anti-OCIAD1 Antibody

OCIA domain-containing protein 1, also known as Ovarian carcinoma immunoreactive antigen, and encoded by the gene name OCIAD1 or OCIA, was identified via immunoscreening of an ovarian carcinoma cDNA library from ovarian cancer patients. expressed in multiple tissues including ovary, placenta, brain, testis, prostate, and mammary gland. Two isoforms of OCIAD1 are known to exist; isoform 1 is highly expressed in multiple tissues including ovary, placenta, brain, testis, prostate, and mammary gland while isoform 2 is restricted to the central nervous system. OCIAD1 is a transmembrane protein whose overexpression in HEY ovarian cancer cells increased lysophosphatidic acid-(LPA-)induced, but not basal level cell adhesion to extracellular matrix proteins collagen I and laminin10/11. This adhesion is not blocked by LY294002 and GF109203X, suggesting that OCIAD1 does not use protein kinase C and PI3 kinase signaling pathways to exert its effect on adhesion

Epitope: C-terminus

KLH-conjugated synthetic peptide corresponding to the C-terminus of human OCIAD1.

Anti-OCIAD1 Antibody detects level of OCIAD1 & has been published & validated for use in OCIAD1.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

Evaluated by Western Blotting in HEK293 cell lysate.

Western Blotting Analysis: 2 μg/mL of this antibody detected OCIAD1 in HEK293 cell lysate.

~27 kDa observed. Uncharacterized bands may be observed in some lysate(s).

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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