产品名称
抗-KLF15抗体, 1.0 mg/mL, from rabbit
biological source
rabbit
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human
species reactivity (predicted by homology)
primate (based on 100% sequence homology), bat (based on 100% sequence homology), baboon (based on 100% sequence homology), chimpanzee (based on 100% sequence homology), monkey (based on 100% sequence homology)
concentration
1.0 mg/mL
technique(s)
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... KLF15(28999)
Application
研究类别
细胞凋亡 & 癌症
细胞凋亡 & 癌症
免疫组化分析：代表性批次的1：50的稀释液在人肝脏组织中检测到KLF15。
抗KLF15抗体可检测KLF15的水平&已发表& 经验证可用于KLF15。
研究子类别
凋亡-附加
凋亡-附加
Analysis Note
通过蛋白质印迹对人骨骼肌组织裂解液进行了评估。
蛋白质印迹分析：0.5 µg/mL的该抗体在10 µg 人骨骼肌组织裂解液中检测到KLF15。
蛋白质印迹分析：0.5 µg/mL的该抗体在10 µg 人骨骼肌组织裂解液中检测到KLF15。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
KLF15，也称为Krueppel样因子15，富含肾脏的Krueppel样因子，由基因KLF15/KKLF编码，是一种转录调节因子，可影响多种发育和细胞系统中的表达。这些包括神经胶质细胞分化，心脏昼夜节律表达调节，足细胞分化，肾小球脏层上皮细胞分化，葡萄糖转运和肽基赖氨酸乙酰化的负调节。KLF15在肝脏、骨骼肌、心肌细胞和肾细胞中高表达。KLF15是非缺血性心肌病、肾小球疾病和主动脉瘤患者的生物标志物。在此类患者中，KLF15表达严重下调。KLF15缺乏会影响心律，并可能在室性心律失常和心脏病理状况中起作用。
观察值〜46 kDa
Immunogen
对应于人KLF15的KLH偶联线性肽。
表位：未知
Physical form
亲和纯化
在含 0.1 M Tris-甘氨酸（pH 7.4），150 mM NaCl 和 0.05％ 叠氮化钠的缓冲液中的纯化的兔多克隆抗体。
Preparation Note
自收到之日起，在 2-8°C 条件下可稳定保存1年
未找到合适的产品？
试试我们的产品选型工具.
存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Yue-Tong Guo et al.
Journal of the American Heart Association, 10(16), e020554-e020554 (2021-08-06)
Background Adventitial remodeling is a pathological hallmark of hypertension that results in target organ damage. Activated adventitial fibroblasts have emerged as critical regulators in this process, but the precise mechanism remains unclear. Methods and Results Interleukin 11 (IL-11) knockout and
Xiangchen Gu et al.
Kidney international, 92(5), 1178-1193 (2017-06-28)
Large epidemiological studies clearly demonstrate that multiple episodes of acute kidney injury contribute to the development and progression of kidney fibrosis. Although our understanding of kidney fibrosis has improved in the past two decades, we have limited therapeutic strategies to
Yiqing Guo et al.
Journal of the American Society of Nephrology : JASN, 29(10), 2529-2545 (2018-08-26)
Podocyte injury is the hallmark of proteinuric kidney diseases, such as FSGS and minimal change disease, and destabilization of the podocyte's actin cytoskeleton contributes to podocyte dysfunction in many of these conditions. Although agents, such as glucocorticoids and cyclosporin, stabilize
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持