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主要文件

ABC152

Sigma-Aldrich

Anti-Annexin A2 Antibody

from rabbit, purified by affinity chromatography

别名:

Annexin A2, Annexin II, Annexin-2, Calpactin I heavy chain, Calpactin-1 heavy chain, Chromobindin-8, Lipocortin II, Placental anticoagulant protein IV, PAP-IV, Protein I, p36

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

rabbit

抗体形式

purified antibody

抗体产品类型

primary antibodies

克隆

polyclonal

纯化方式

affinity chromatography

种属反应性

rat, human

种属反应性(根据同源性预测)

primate (based on 100% sequence homology), mouse (based on 100% sequence homology), bovine (based on 100% sequence homology), porcine (based on 100% sequence homology), canine (based on 100% sequence homology)

技术

immunohistochemistry: suitable (paraffin)
western blot: suitable

NCBI登记号

UniProt登记号

运输

wet ice

靶向翻译后修饰

unmodified

基因信息

human ... ANXA2(302)

一般描述

Annexin A2 is known by several other names including: Annexin II, Calpactin I heavy chain, Chromobindin-8, Lipocortin II and Placental anticoagulant protein IV. Annexin A2 is a calcium-regulated membrane-binding protein that binds two calcium ions with high affinity. Annexin A2′s affinity for calcium is enhanced by anionic phospholipids. Annexin A2 has been shown to bind to human cytomegalvirus (HCMV) and may be involved in heat-stress response and apoptosis.

特异性

This antibody recognizes the Annexin 1 repeat domain of Annexin A2.

免疫原

Epitope: Annexin 1 repeat domain
KLH-conjugated linear peptide corresponding to Annexin 1 repeat domain of human Annexin A2.

应用

Anti-Annexin A2 is an antibody targeting the Annexin A2 protein, validated for use in WB & IHC.
Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected Annexin A2 in human and rat colon tissues.
Research Category
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional

质量

Evaluated by Western Blotting in A549 cell lysate.

Western Blotting Analysis: 1.0 µg/mL of this antibody detected Annexin A2 in 10 µg of A549 cell lysate.

目标描述

~36 kDa observed

外形

Protein A purified
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

储存及稳定性

Stable for 1 year at 2-8°C from date of receipt.

分析说明

Control
A549 cell lysate

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Shahzadi Noreen et al.
Proteomics. Clinical applications, 14(2), e1900078-e1900078 (2019-11-21)
An early and accurate diagnosis of ovarian carcinoma (OC) may reduce morbidity and mortality of the patients. To improve the clinical outcome in OC patients, the present study is aimed at identifying robust biomarkers for early OC diagnosis. EXPERIMENTAL DESIGN: In

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