Anti-NOXA1 Antibody

NOXA1 (NADPH oxidase activator 1; Antigen NY-CO-31; NCF2-like protein; P67phox-like factor; p51-nox) is an activator of the NADPH oxidase NOX1. It contains multiple domains, including four TPR repeats which facilitate interaction with RAC1, and one SH3 domain that binds to NOXO1. NOXA1 interacts with NOXO1, RAC1, NOX1, and CYBA to form a multi-protein complex that produces reactive oxygen species for important cellular processes such as oxygen sensing, hormone biosynthesis, and signal transduction. NOXA1 is found in pancreas, spleen, liver, prostate, colon, and small intestine.

No homology to Rat or Mouse detected.

KLH-conjugated linear peptide corresponding to human NOXA1.

Detect NOXA1 using this Anti-NOXA1 Antibody validated for use in Western Blotting.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

Evaluated by Western Blot in Human Colon tissue lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected NOXA1 in 10 µg of human colon tissue lysate.

~51 kDa observed

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stable for 1 year at 2-8°C from date of receipt.

Control
Human colon tissue lysate

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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