ABC10
抗-Megf10抗体
from rabbit, purified by affinity chromatography
别名:
Multiple epidermal growth factor-like domains protein 10, Multiple EGF-like domains protein 10
产品名称
抗-Megf10抗体, from rabbit, purified by affinity chromatography
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
mouse
technique(s)
immunofluorescence: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
mouse ... Megf10(70417)
Analysis Note
对照
小鼠视网膜组织裂解物
小鼠视网膜组织裂解物
通过蛋白质印迹在小鼠视网膜组织裂解物中进行了评估。
蛋白质印迹分析：1 µg/mL的该抗体在10 µg小鼠视网膜组织裂解物中检测到Megf10。
蛋白质印迹分析：1 µg/mL的该抗体在10 µg小鼠视网膜组织裂解物中检测到Megf10。
Application
使用经验证可用于WB& IF的抗Megf10检测Megf10蛋白。
免疫荧光分析： 独立实验室在P7尾部脑组织和视网膜细胞中使用了代表性批次。 图片来自哈佛大学Joshua Sanes博士的实验室。
研究子类别
凋亡-附加
凋亡-附加
研究类别
细胞凋亡 & 癌症
细胞凋亡 & 癌症
Biochem/physiol Actions
其他同源性： 大鼠（98%序列同源性）和人（92%序列同源性）。
该抗体可识别胞质结构域的Megf10。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
多个表皮生长因子样结构域蛋白10（Megf10）是具有多个EGF样细胞外结构域的1型跨膜蛋白。Megf10在大脑中高度表达，在凋亡细胞的吞噬作用中起重要作用。可以通过Megf10与ATP结合盒转运蛋白（ABCA1）的相互作用来发挥此作用。先前的研究表明，Megf10可能参与了大脑中淀粉样β肽的摄取。因此，Megf10可能在阿尔茨海默’病中起作用。
观测值〜130 kDa
Immunogen
组氨酸标记的重组蛋白，对应于小鼠Megf10的胞质结构域。
表位：细胞质结构域
Other Notes
浓度：请参考批次特异性浓缩物的分析证书。
Physical form
亲和纯化
在含 0.1 M Tris-甘氨酸（pH 7.4），150 mM NaCl 和 0.05％ 叠氮化钠的缓冲液中的纯化的兔多克隆抗体。
Preparation Note
自收到之日起，在 2-8°C 条件下可稳定保存1年
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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