推荐产品
生物来源
rabbit
质量水平
抗体形式
serum
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
mouse
制造商/商品名称
Chemicon®
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
mouse ... Cyp2B10(13088)
一般描述
CYP2b10（细胞色素P450，家族2，亚家族b，多肽10）是单加氧酶的细胞色素P450超家族的成员，其催化涉及药物代谢和胆固醇，类固醇和其他脂质合成的许多反应。
特异性
AB9916对CYP2b10具有特异性。
免疫原
表位：AA I182 – T205
重组2b10
应用
该抗CYP2b10抗体经过验证可用于WB中检测CYP2b10。
质量
已通过免疫印迹进行常规评估。
目标描述
58kDa
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
Shinhee Park et al.
Acta pharmaceutica Sinica. B, 6(5), 475-491 (2016-10-07)
Intestine is responsible for the biotransformation of many orally-exposed chemicals. The constitutive androstane receptor (CAR/Nr1i3) is known to up-regulate many genes encoding drug-metabolizing enzymes and transporters (drug-processing genes/DPGs) in liver, but less is known regarding its effect in intestine. Sixty-day-old
Joseph A Cichocki et al.
The Journal of pharmacology and experimental therapeutics, 361(1), 17-28 (2017-02-06)
Lifestyle factors and chronic pathologic states are important contributors to interindividual variability in susceptibility to xenobiotic-induced toxicity. Nonalcoholic fatty liver disease (NAFLD) is an increasingly prevalent condition that can dramatically affect chemical metabolism. We examined the effect of NAFLD on
Cindy Yanfei Li et al.
Drug metabolism and disposition: the biological fate of chemicals, 44(7), 1038-1049 (2015-11-19)
The xenobiotic-sensing transcription factors (xeno-sensors) AhR, CAR, and PXR upregulate the expression of many drug-processing genes (DPGs) in liver. Previous studies have unveiled profound changes in the basal expression of DPGs during development; however, knowledge on the ontogeny of the
Hemantkumar Chavan et al.
The Journal of biological chemistry, 290(12), 7871-7886 (2015-01-28)
Although endogenous mechanisms that negatively regulate cytochrome P450 (P450) monooxygenases in response to physiological and pathophysiological signals are not well understood, they are thought to result from alterations in the level of endogenous metabolites, involved in maintaining homeostasis. Here we
Kentaro Nobutani et al.
Pharmacology research & perspectives, 5(5) (2017-10-04)
Herbal medicines and natural products used for maintenance of health or treatment of diseases have many biological effects, including altering the pharmacokinetics and metabolism of other medications. Daikenchuto (TU-100), an aqueous extract of ginger, ginseng, and Japanese green pepper fruit
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