推荐产品
生物来源
rabbit
质量水平
抗体形式
serum
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
mouse, rat, human
制造商/商品名称
Chemicon®
技术
immunoprecipitation (IP): suitable
western blot: suitable
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... QKI(9444)
一般描述
QKI 是一种RNA结合蛋白，在髓鞘形成中起主导作用。通过调节pre-mRNA剪接、mRNA输出、mRNA稳定性和蛋白质翻译起作用。它通过可变剪接调节。
特异性
QKI-7 （Quaking 蛋白）该抗体识别~42 kDa蛋白。
免疫原
来自小鼠QKI-7的合成肽。
应用
抗-QKI-7抗体是针对QKI-7的抗体，可用于IP & WB。
研究子类别
发育神经科学
RNA结合蛋白（RBP）
发育神经科学
RNA结合蛋白（RBP）
研究类别
神经科学
神经科学
外形
液体。
血清
储存及稳定性
自收到之日起，在 -20°:C 以未稀释的等分试样可保存 12 个月。应避免反复冻/融循环。
分析说明
对照
阳性对照：神经胶质细胞、星形胶质细胞和少突胶质细胞
阳性对照：神经胶质细胞、星形胶质细胞和少突胶质细胞
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Valerie Bríd O'Leary et al.
Oncotarget, 8(45), 78397-78409 (2017-11-08)
Generated by Quaking (QKI), circular RNAs (circRNAs) are newly recognised non-coding RNA (ncRNA) members characterised by tissue specificity, increased stability and enrichment within exosomes. Studies have shown that ionizing radiation (IR) can influence ncRNA transcription. However, it is unknown whether
Zhejia Zhang et al.
Oncology letters, 15(4), 5841-5848 (2018-03-21)
Thyroid cancer is the most frequently occurring type of endocrine tumor, with a rapidly increasing incidence rate. MicroRNA (miR)-574-5p is a candidate oncogene in various types of cancer. The present study identified that miR-574-5p affected the cell cycle distribution and
Kristina Sakers et al.
Nature communications, 12(1), 1537-1537 (2021-03-23)
Quaking RNA binding protein (QKI) is essential for oligodendrocyte development as myelination requires myelin basic protein mRNA regulation and localization by the cytoplasmic isoforms (e.g., QKI-6). QKI-6 is also highly expressed in astrocytes, which were recently demonstrated to have regulated
Ruben G de Bruin et al.
Nature communications, 7, 10846-10846 (2016-04-01)
A hallmark of inflammatory diseases is the excessive recruitment and influx of monocytes to sites of tissue damage and their ensuing differentiation into macrophages. Numerous stimuli are known to induce transcriptional changes associated with macrophage phenotype, but posttranscriptional control of
Xinyun Chen et al.
Nature communications, 12(1), 89-89 (2021-01-06)
The RNA-binding protein QKI belongs to the hnRNP K-homology domain protein family, a well-known regulator of pre-mRNA alternative splicing and is associated with several neurodevelopmental disorders. Qki is found highly expressed in developing and adult hearts. By employing the human
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