推荐产品
生物来源
rabbit
质量水平
抗体形式
serum
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
mouse, rat, human
制造商/商品名称
Chemicon®
技术
immunoprecipitation (IP): suitable
western blot: suitable
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... QKI(9444)
一般描述
QKI 是一种RNA结合蛋白，在髓鞘形成中起主导作用。通过调节pre-mRNA剪接、mRNA输出、mRNA稳定性和蛋白质翻译起作用。它通过可变剪接调节。
特异性
QKI-6 （Quaking 蛋白）该抗体识别~38 kDa蛋白。
免疫原
来自小鼠QKI-6的合成肽。
应用
QKI-6抗体可检测QKI-6水平 & 已发表 & 经验证可用于IP & WB。
研究子类别
发育神经科学
RNA结合蛋白（RBP）
发育神经科学
RNA结合蛋白（RBP）
研究类别
神经科学
神经科学
外形
液体。
血清
储存及稳定性
自收到之日起，在 -20°C 以未稀释的等分试样可保存 12 个月。应避免反复冻/融循环。
分析说明
对照
阳性对照：神经胶质细胞、星形胶质细胞和少突胶质细胞
阳性对照：神经胶质细胞、星形胶质细胞和少突胶质细胞
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Zhengyi Zhang et al.
Nature communications, 10(1), 4397-4397 (2019-09-29)
Strand-selection is the final step of microRNA biogenesis in which functional mature miRNAs are generated from one or both arms of precursor. The preference of strand-selection is diverse during development and tissue formation, however, its pathological effect is still unknown.
Ruben G de Bruin et al.
Epigenomes, 4(1) (2020-02-13)
In the pathophysiologic setting of acute and chronic kidney injury, the excessive activation and recruitment of blood-borne monocytes prompts their differentiation into inflammatory macrophages, a process that leads to progressive glomerulosclerosis and interstitial fibrosis. Importantly, this differentiation of monocytes into
Seula Shin et al.
Nature communications, 12(1), 3005-3005 (2021-05-23)
Defective cholesterol biosynthesis in eye lens cells is often associated with cataracts; however, how genes involved in cholesterol biosynthesis are regulated in lens cells remains unclear. Here, we show that Quaking (Qki) is required for the transcriptional activation of genes
Zhejia Zhang et al.
Oncology letters, 15(4), 5841-5848 (2018-03-21)
Thyroid cancer is the most frequently occurring type of endocrine tumor, with a rapidly increasing incidence rate. MicroRNA (miR)-574-5p is a candidate oncogene in various types of cancer. The present study identified that miR-574-5p affected the cell cycle distribution and
Kristina Sakers et al.
Nature communications, 12(1), 1537-1537 (2021-03-23)
Quaking RNA binding protein (QKI) is essential for oligodendrocyte development as myelination requires myelin basic protein mRNA regulation and localization by the cytoplasmic isoforms (e.g., QKI-6). QKI-6 is also highly expressed in astrocytes, which were recently demonstrated to have regulated
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