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Merck
CN

AB9342

Anti-CNPase Antibody

Chemicon®, from chicken

别名:

Anti-CNP1, Anti-HLD20

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
immunocytochemistry
immunohistochemistry
Species reactivity:
mouse, human
Citations:
7
Technique(s):
immunocytochemistry: suitable
immunohistochemistry: suitable
Uniprot accession no.:
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产品名称

Anti-CNPase Antibody, Chemicon®, from chicken

biological source

chicken

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse, human

manufacturer/tradename

Chemicon®

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... CNP(1267)

Application

Anti-CNPase Antibody is an antibody against CNPase for use in IC, IH.
Immunohistochemistry: 1:1000 using 2% paraformaldehyde fixed tissues.

Immunocytochemistry: 1:1000 using 2% paraformaldehyde fixed cells.

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neuronal & Glial Markers

Biochem/physiol Actions

Recognizes CNPase (2′, 3′-cyclic nucleotide phosphodiesterase).

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

Synthetic peptide from human/mouse CNPase.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Physical form

Affinity purified chicken IgY. Liquid in PBS, pH 7.2 with 0.02% sodium azide.

Preparation Note

Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt. It is recommended that you store the antibody in the dark.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


分析证书(COA)

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Vlad Dionisie et al.
International journal of molecular sciences, 22(14) (2021-07-25)
In recent years, escitalopram (ESC) has been suggested to have different mechanisms of action beyond its well known selective serotonin reuptake inhibition. The aim of this study is to investigate the effects of escitalopram on oxidative stress, apoptosis, brain-derived neurotrophic
Jennifer Patritti Cram et al.
eLife, 11 (2022-03-22)
Neurofibromatosis type 1 (NF1) is characterized by nerve tumors called neurofibromas, in which Schwann cells (SCs) show deregulated RAS signaling. NF1 is also implicated in regulation of cAMP. We identified the G-protein-coupled receptor (GPCR) P2ry14 in human neurofibromas, neurofibroma-derived SC
Melissa R Perrino et al.
Life science alliance, 7(5) (2024-03-09)
Plexiform neurofibromas (PNFs) are nerve tumors caused by loss of NF1 and dysregulation of RAS-MAPK signaling in Schwann cells. Most PNFs shrink in response to MEK inhibition, but targets with increased and durable effects are needed. We identified the anaphylatoxin
Kae M Pusic et al.
PloS one, 16(8), e0255778-e0255778 (2021-08-14)
Extracellular vesicles secreted from IFNγ-stimulated rat dendritic cells (referred to here as IFNγ-DC-EVs) contain miRNAs which promote myelination (including but not limited to miR-219), and preferentially enter oligodendrocytes in brain slice cultures. IFNγ-DC-EVs also increase myelination when nasally administered to
Aditya Rayasam et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 38(32), 7058-7071 (2018-07-01)
T cells continuously sample CNS-derived antigens in the periphery, yet it is unknown how they sample and respond to CNS antigens derived from distinct brain areas. We expressed ovalbumin (OVA) neoepitopes in regionally distinct CNS areas (Cnp-OVA and Nes-OVA mice)

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