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Merck
CN

AB9276

Anti-Filamin B Antibody

Chemicon®, from rabbit

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关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
western blot
Species reactivity:
human
Citations:
7
Technique(s):
western blot: suitable
Uniprot accession no.:
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产品名称

Anti-Filamin B Antibody, Chemicon®, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... FLNB(2317)

Analysis Note

Control
HeLa cells

Application

Anti-Filamin B Antibody detects level of Filamin B & has been published & validated for use in WB.
Research Category
Cell Structure
Research Sub Category
Cytoskeleton
Western blot: 0.1 μg/mL on HeLa cell lysate and LAN-1 human neuroblastoma cell lysate. 0.25-0.5 μg/mL on HuVec cell lysate. Reacts with the ~278 kDa Filamin B protein.

Optimal working dilutions must be determined by the end user.

Biochem/physiol Actions

Filamin B

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Immunogen

Synthetic peptide from human filamin B. The immunogen peptide corresponds to a sequence near the hinge 2 region of Filamin B (near C-term) and is not present in the two C-terminally truncated splice variants of Filamin B (Var-2 and Var-3). The peptide shows no significant similarity to other antigens in the human protein database including Filamin A or Filamin C.

Physical form

Affinity purified immunoglobulin. Liquid in 0.02 M PBS, 0.25 M NaCl containing 0.1% sodium azide.

Preparation Note

Maintain at 2-8°C in undiluted aliquots for up to 6 months after date of receipt.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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存储类别

10 - Combustible liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Lang-Ming Chi et al.
Molecular & cellular proteomics : MCP, 8(7), 1453-1474 (2009-03-20)
Oral squamous cell carcinoma (OSCC) remains one of the most common cancers worldwide, and the mortality rate of this disease has increased in recent years. No molecular markers are available to assist with the early detection and therapeutic evaluation of
Luís Korrodi-Gregório et al.
PloS one, 11(11), e0165973-e0165973 (2016-11-05)
Lung cancer is a serious health problem and the leading cause of cancer death worldwide. The standard use of cell lines as in vitro pre-clinical models to study the molecular mechanisms that drive tumorigenesis and access drug sensitivity/effectiveness is of
Philip B Daniel et al.
Human mutation, 33(4), 665-673 (2011-12-23)
Dominant missense mutations in FLNB, encoding the actin-cross linking protein filamin B (FLNB), cause a broad range of skeletal dysplasias with varying severity by an unknown mechanism. Here these FLNB mutations are shown to cluster in exons encoding the actin-binding
Frances Willenbrock et al.
Biophysical journal, 105(5), 1110-1122 (2013-09-10)
Shear flow assays are used to mimic the influence of physiological shear force in diverse situations such as leukocyte rolling and arrest on the vasculature, capture of nanoparticles, and bacterial adhesion. Analysis of such assays usually involves manual counting, is
Xian Zhao et al.
The Journal of biological chemistry, 299(7), 104851-104851 (2023-05-24)
Sphingosine 1-phosphate receptor 1 (S1PR1) is a G protein-coupled receptor essential for vascular development and postnatal vascular homeostasis. When exposed to sphingosine 1-phosphate (S1P) in the blood of ∼1 μM, S1PR1 in endothelial cells retains cell-surface localization, while lymphocyte S1PR1 shows

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