产品名称
抗胰岛素降解酶抗体, serum, Chemicon®
biological source
rabbit
conjugate
unconjugated
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
rat
packaging
antibody small pack of 25 μL
manufacturer/tradename
Chemicon®
technique(s)
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
target post-translational modification
unmodified
Quality Level
Gene Information
rat ... Ins1(24505)
Analysis Note
经过测试
Application
抗胰岛素降解酶抗体是针对胰岛素降解酶的抗体，用于 WB。
研究子类别
神经退行性疾病
神经退行性疾病
研究类别
神经科学
神经科学
蛋白质印迹：1：10,000-1：20,000.该抗体识别大鼠肝组织裂解液中约 110 kDa 的蛋白质。
最佳工作稀释度必须由最终用户确定。
最佳工作稀释度必须由最终用户确定。
Biochem/physiol Actions
胰岛素降解酶（IDE）。 由于免疫原序列同源性，预计该抗体也与人和小鼠反应。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
Immunogen
来自大鼠 IDE 的合成肽。
Other Notes
请参考特定批次的数据表。
Physical form
兔血清。 液体。
Preparation Note
自收到之日起，在 -20°C 以未稀释的等分试样可保存 6 个月。应避免反复冻/融循环。
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
未找到合适的产品？
试试我们的产品选型工具.
存储类别
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Beatriz Merino et al.
Metabolism: clinical and experimental, 113, 154352-154352 (2020-09-12)
The insulin-degrading enzyme (IDE) is a metalloendopeptidase with a high affinity for insulin. Human genetic polymorphisms in Ide have been linked to increased risk for T2DM. In mice, hepatic Ide ablation causes glucose intolerance and insulin resistance when mice are
Carlos M González-Casimiro et al.
Cells, 10(9) (2021-09-29)
Insulin-degrading enzyme (IDE) is a highly conserved and ubiquitously expressed Zn2+-metallopeptidase that regulates hepatic insulin sensitivity, albeit its regulation in response to the fasting-to-postprandial transition is poorly understood. In this work, we studied the regulation of IDE mRNA and protein
Miriam Corraliza-Gómez et al.
Cells, 11(2) (2022-01-22)
The insulin-degrading enzyme (IDE) is a zinc-dependent metalloendopeptidase that belongs to the M16A metalloprotease family. IDE is markedly expressed in the brain, where it is particularly relevant due to its in vitro amyloid beta (Aβ)-degrading activity. The subcellular localization of
Enrique Jurado-Ruiz et al.
Scientific reports, 9(1), 11311-11311 (2019-08-07)
Dietary composition plays an important role in the pathophysiology of type 2 diabetes. Monounsaturated fatty acid consumption has been positively associated with improved insulin sensitivity and β-cell function. We examined whether an extra virgin olive oil (EVOO) high fat diet
Jéssica Taday et al.
Metabolites, 14(3) (2024-03-27)
Astrocytes play fundamental roles in the maintenance of brain homeostasis. The dysfunction of these cells is widely associated with brain disorders, which are often characterized by variations in the astrocyte protein markers GFAP and S100B, in addition to alterations in
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持