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AB6021

Sigma-Aldrich

Anti-Stabilin-1 Antibody, CT

from rabbit

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别名:
Fasciclin, EGF-like, laminin-type EGF-like and link domain-containing scavenger receptor 1, MS-1 antigen, common lymphatic endothelial and vascular endothelial receptor-1, fasciclin egf-like, laminin-type egf-like, and link domain-containing scavenger re
UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

rabbit

质量水平

抗体形式

unpurified

抗体产品类型

primary antibodies

克隆

polyclonal

种属反应性

human

技术

immunofluorescence: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable

UniProt登记号

运输

wet ice

靶向翻译后修饰

unmodified

基因信息

human ... STAB1(23166)

一般描述

Stabilin-1 and Stabilin-2 constitute a novel family of fasciclin domain-containing hyaluronan receptor homologs that may play a role in cell-cell and cell-extracellular matrix interactions in vascular function and inflammatory processes. Stabilin-1 is a transmembrane protein, expressed in endothelial cells within the sinusoidal regions of liver, spleen, and lymph tissues as well as macrophages. Stabilin-2 is absent from the latter (Politz, 2002).

特异性

Other notable species homologies include mouse (87%) and rat (83%).
The antibody recognizes the C-terminus of Stabilin-1 within the cytoplasmic region of a cell.

免疫原

Epitope: C-terminus
GST-tagged recombinant protein corresponding to the C-terminus of human Stabilin-1.

应用

Anti-Stabilin-1 Antibody, C-terminus is an antibody against Stabilin-1 for use in WB, IH(P) & IF.
Immunohistochemistry Analysis: 1:500 dilution from a previous lot detected Stabilin-1 in human placental tertiary villi.
Immunofluorescence Analysis: A previous lot of Anti-Stabilin-1, C-terminus was shown to positively stain using immunofluorescence techniques (Kzhyshkowska, 2008).
Research Category
Cell Structure
Research Sub Category
Adhesion (CAMs)

质量

Evaluated by Western blot in HUVEC lysate.
Western blot Analysis: 1:1,000 dilution of this antibody detected Stabilin-1 on 10 µg of HUVEC lysate.

目标描述

~ 275 kDa

外形

Unpurified
Format: Unpurified
Unpurified rabbit polyclonal in serum with 0.05% sodium azide.

储存及稳定性

Stable for 1 year at -20°C from date of receipt if stored in undiluted aliquots.
Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

分析说明

Control
HUVEC lysate.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

WGK

WGK 1


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