推荐产品
生物来源
rabbit
质量水平
抗体形式
affinity purified immunoglobulin
抗体产品类型
primary antibodies
克隆
polyclonal
纯化方式
affinity chromatography
种属反应性
human, monkey
制造商/商品名称
Chemicon®
技术
immunocytochemistry: suitable
immunohistochemistry: suitable
immunoprecipitation (IP): suitable
western blot: suitable
UniProt登记号
运输
wet ice
靶向翻译后修饰
unmodified
基因信息
human ... APP(351)
特异性
Amyloid precursor protein (APP), domain 770, but not APP751 or APP695.
免疫原
Epitope: OX2 Domain 770
Synthetic peptide corresponding to the OX2 domain of APP770.
应用
Anti-Amyloid Precursor Protein Antibody, Domain 770 detects level of Amyloid Precursor Protein & has been published & validated for use in IP, WB, IC, IH.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Neurodegenerative Diseases
Western Blot
Immunohistochemistry on cold methanol fixed tissues.
Immunocytochemistry
Immunoprecipitation
Optimal working dilutions must be determined by the end user.
Immunohistochemistry on cold methanol fixed tissues.
Immunocytochemistry
Immunoprecipitation
Optimal working dilutions must be determined by the end user.
外形
Affinity purified immunoglobulin. Liquid in TRIS-buffered saline with 0.01% sodium azide.
储存及稳定性
Maintain at 2-8°C in undiluted aliquots for up to 6 months.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
WGK
WGK 2
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Hitomi Komura et al.
iScience, 13, 452-477 (2019-03-05)
We identified ∼30-mer amyloid-β protein (Aβ) assemblies, termed amylospheroids, from brains of patients with Alzheimer disease (AD) as toxic entities responsible for neurodegeneration and showed that Na+,K+-ATPase α3 (NAKα3) is the sole target of amylospheroid-mediated neurodegeneration. However, it remains unclear
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