产品名称
Anti-Presenilin 1 Antibody, Chemicon®, from chicken
biological source
chicken
conjugate
unconjugated
antibody form
affinity purified immunoglobulin
antibody product type
primary antibodies
clone
polyclonal
purified by
affinity chromatography
species reactivity
human, mouse, rat
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
dry ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... PSEN1(5663)
Immunogen
Synthetic peptides from human Presenilin 1.
Application
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurodegenerative Diseases
Neurodegenerative Diseases
Detect Presenilin 1 using this Anti-Presenilin 1 Antibody validated for use in ELISA & WB.
Immunoblotting: 1:1,000-1:4,000. To minimize background staining it is suggested that you include a higher content of detergent (Tween-20) in your dilution and washing solutions.
Immunohistochemistry: not tested. It is recommended that you try the antibody at 1:50-1:500.
ELISA: 1:1,000-1:4,000
Optimal working dilutions must be determined by the end user.
Immunohistochemistry: not tested. It is recommended that you try the antibody at 1:50-1:500.
ELISA: 1:1,000-1:4,000
Optimal working dilutions must be determined by the end user.
Biochem/physiol Actions
Presenilin 1
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Other Notes
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.
Physical form
Affinity purified immunoglobulin. Liquid in PBS containing 0.02% sodium azide.
Preparation Note
Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Xike Qin et al.
The Journal of biological chemistry, 291(42), 22276-22287 (2016-09-01)
Accumulation of amyloid-β peptide (Aβ) in the brain is regarded as central to Alzheimer's disease (AD) pathogenesis. Aβ is generated by a sequential cleavage of amyloid precursor protein (APP) by β-secretase 1 (BACE-1) followed by γ-secretase. BACE-1 cleavage of APP
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