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Merck
CN
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文件

AB5727

Sigma-Aldrich

抗-Sox10抗体

Chemicon®, from rabbit

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UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

rabbit

质量水平

抗体形式

affinity purified immunoglobulin

克隆

polyclonal

纯化方式

affinity chromatography

种属反应性

mouse

制造商/商品名称

Chemicon®

技术

western blot: suitable

NCBI登记号

UniProt登记号

运输

wet ice

靶向翻译后修饰

unmodified

一般描述

Sox 10是转录因子家族的成员,参与调节胚胎发育和确定细胞去向。编码蛋白在与其他蛋白形成蛋白复合物后可作为转录激活因子。该蛋白作为核细胞质穿梭蛋白,在神经嵴和周围神经系统发育中起重要作用。sox10在多能神经嵴干细胞中表达,其表达在其分化过程中下调。该基因的突变与瓦登堡-沙赫病和瓦登堡-赫氏病有关。

特异性

Sox10。 免疫原序列与Sox8和Sox9有70%的保守性,因此抗体可能会与这些蛋白产生交叉反应。

免疫原

Sox10的合成肽。

应用

抗-Sox10抗体检测Sox10水平,已发布,经验证可用于WB。
研究子类别
发育神经科学

神经&胶质标志物
研究类别
神经科学
蛋白质印迹:0.1-0.5 μg/mL,对胎鼠脑组织裂解液使用ECL。该抗体与~60 kDa的蛋白反应。根据所使用的样品,还可能会出现一个 〜120 kDa 的额外的条带。

最佳工作稀释度必须由最终用户进行确定。

目标描述

大约55 kDa

联系

替代:AB5774

外形

亲和纯化的免疫球蛋白。 液体。

储存及稳定性

接收后,以未稀释的等分试样在+2-8°C下保存长达6个月。

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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