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AB5447

Sigma-Aldrich

抗原肌球蛋白抗体,5NM1 和 5NM2

Chemicon®, from sheep

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

sheep

质量水平

抗体形式

affinity purified immunoglobulin

抗体产品类型

primary antibodies

克隆

polyclonal

纯化方式

affinity chromatography

种属反应性

mouse, rat

制造商/商品名称

Chemicon®

技术

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

UniProt登记号

运输

dry ice

靶向翻译后修饰

unmodified

基因信息

human ... TPM3(7170)

特异性

识别原肌球蛋白5NM1和5NM2。

免疫原

对应于来自原肌球蛋白γ基因的9d外显子的合成肽。
表位:5NM1和5NM2。

应用

使用经验证可用于WB、IC、IH的该抗原肌球蛋白2抗体5NM1 & 5NM2 检测原肌球蛋白。
研究子类别
肌肉生理学
研究类别
代谢
蛋白质印迹:1:100-1:500。 该抗体与29-30kDa的条带反应。

免疫细胞化学:1:100-1:500
免疫组化:1:100-1:500

最佳工作稀释度必须由最终用户确定。

外形

溶于PBS的亲和纯化免疫球蛋白(液体)。

储存及稳定性

自收到之日起,在 -20°C 以未稀释的等分试样可保存 6 个月。应避免反复冻/融循环。

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Sawako Yamashiro et al.
The Journal of biological chemistry, 289(17), 11616-11629 (2014-03-20)
Tropomodulins (Tmods) are F-actin pointed end capping proteins that interact with tropomyosins (TMs) and cap TM-coated filaments with higher affinity than TM-free filaments. Here, we tested whether differences in recognition of TM or actin isoforms by Tmod1 and Tmod3 contribute
David S Gokhin et al.
Molecular biology of the cell, 26(9), 1699-1710 (2015-02-27)
Short, uniform-length actin filaments function as structural nodes in the spectrin-actin membrane skeleton to optimize the biomechanical properties of red blood cells (RBCs). Despite the widespread assumption that RBC actin filaments are not dynamic (i.e., do not exchange subunits with
David S Gokhin et al.
The Journal of cell biology, 194(1), 105-120 (2011-07-06)
The sarcoplasmic reticulum (SR) serves as the Ca(2+) reservoir for muscle contraction. Tropomodulins (Tmods) cap filamentous actin (F-actin) pointed ends, bind tropomyosins (Tms), and regulate F-actin organization. In this paper, we use a genetic targeting approach to examine the effect
Maria Sckolnick et al.
Molecular biology of the cell, 27(19), 2889-2897 (2016-08-19)
Tropomyosin (Tpm) isoforms decorate actin with distinct spatial and temporal localization patterns in cells and thus may function to sort actomyosin processes by modifying the actin track affinity for specific myosin isoforms. We examined the effect of three Tpm isoforms
Salma Pathan-Chhatbar et al.
The Journal of biological chemistry, 293(3), 863-875 (2017-12-02)
The metazoan actin cytoskeleton supports a wide range of contractile and transport processes. Recent studies have shown how the dynamic association with specific tropomyosin isoforms generates actin filament populations with distinct functional properties. However, critical details of the associated molecular

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