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Merck
CN
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主要文件

AB5330

Sigma-Aldrich

Anti-Syntaxin 4 Antibody

Chemicon®, from rabbit

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

rabbit

质量水平

抗体形式

affinity purified immunoglobulin

抗体产品类型

primary antibodies

克隆

polyclonal

纯化方式

affinity chromatography

种属反应性

rat

制造商/商品名称

Chemicon®

技术

western blot: suitable

NCBI登记号

UniProt登记号

运输

wet ice

靶向翻译后修饰

unmodified

基因信息

human ... STX4(6810)

特异性

Recognizes Syntaxin 4.

免疫原

Highly purified corresponding to residues 2-23 of rat or mouse Syntaxin 4 (Accession Q08850).

应用

Research Category
Neuroscience
Research Sub Category
Synapse & Synaptic Biology
This Anti-Syntaxin 4 Antibody is validated for use in WB for the detection of Syntaxin 4.
Western blotting: 0.5-1.0 μg/mL (1:200-1:500) Dilutions should be made using a carrier protein such as BSA (1-3%).


Optimal working dilutions must be determined by the end user.

外形

Affinity purified immunoglobulin. Lyophilized from PBS, pH 7.4, containing 1% BSA and 0.025% sodium azide. Reconstitute with 200 μL of sterile distilled water. Centrifuge antibody preparation before use (10,000 x g for 5 min).

储存及稳定性

Maintain lyophilized material at -20°C for up to 6 months. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

分析说明

Control
CONTROL ANTIGEN: Included free of charge with the antibody is 40 μg of control antigen (lyophilized powder). Reconstitute with 100 μL of sterile distilled water. For negative control, preincubate 1 μg of purified peptide with 1 μg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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危险声明

预防措施声明

危险分类

Aquatic Chronic 3

储存分类代码

11 - Combustible Solids

WGK

WGK 3


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Brendan J O'Brien et al.
Molecular vision, 16, 1854-1863 (2010-10-30)
The retina has the demanding task of encoding all aspects of the visual scene within the space of one fixation period lasting only a few hundred milliseconds. To accomplish this feat, information is encoded in specialized parallel channels and passed
Brian S Clark et al.
Development (Cambridge, England), 139(9), 1599-1610 (2012-04-12)
To gain insights into the cellular mechanisms of neurogenesis, we analyzed retinal neuroepithelia deficient for Llgl1, a protein implicated in apicobasal cell polarity, asymmetric cell division, cell shape and cell cycle exit. We found that vertebrate retinal neuroepithelia deficient for
Arlene A Hirano et al.
Visual neuroscience, 24(4), 489-502 (2007-07-21)
Horizontal cells mediate inhibitory feed-forward and feedback communication in the outer retina; however, mechanisms that underlie transmitter release from mammalian horizontal cells are poorly understood. Toward determining whether the molecular machinery for exocytosis is present in horizontal cells, we investigated
Jia Cheng et al.
The Journal of physiology, 591(16), 3935-3947 (2013-06-19)
The group II metabotropic glutamate receptors (group II mGluRs) have emerged as the new drug targets for the treatment of mental disorders like schizophrenia. To understand the potential mechanisms underlying the antipsychotic effects of group II mGluRs, we examined their
Eunjin Oh et al.
Diabetes, 70(12), 2837-2849 (2021-09-25)
Syntaxin 4 (STX4), a plasma membrane-localized SNARE protein, regulates human islet β-cell insulin secretion and preservation of β-cell mass. We found that human type 1 diabetes (T1D) and NOD mouse islets show reduced β-cell STX4 expression, consistent with decreased STX4

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