跳转至内容
Merck
CN

AB5062P

抗囊泡GABA转运蛋白(VGAT)抗体

Chemicon®, from rabbit

别名:

Vesicular Inhibitory Amino Acid Transporter

登录 查看组织和合同定价。

选择尺寸


关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
技术服务
需要帮助?我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助?我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

产品名称

抗囊泡GABA转运蛋白(VGAT)抗体, Chemicon®, from rabbit

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse, monkey, human, rat

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
immunofluorescence: suitable
immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Quality Level

Gene Information

human ... SLC32A1(140679)

Analysis Note

对照
脑组织、大鼠视网膜裂解物
已通过蛋白质印迹对大鼠视网膜裂解物进行了评估。

蛋白质印迹分析:
该抗体的1:500的稀释液在10 μg大鼠视网膜裂解物中检测到囊泡GABA转运蛋白。

Application

免疫组化/免疫荧光
在多聚甲醛固定切片上使用2-20 µg/mL的先前批次。

ELISA:
将先前批次的1:10,000–1:100,000稀释液用于ELISA,每孔使用50-100 ng对照肽(目录号AG379)。

蛋白质印迹:
1-10 µg/ml(化学发光技术)预期的分子量约为55-60 kDa。

最佳工作稀释度必须由最终用户进行确定。
该抗囊泡GABA转运蛋白(VGAT)抗体经验证可用于ELISA、IF、IH、WB检测囊泡GABA转运蛋白(VGAT)。

Biochem/physiol Actions

对囊泡GABA转运蛋白(VGAT)具有特异性。囊泡GABA转运蛋白(unc-47)同源物是525个氨基酸长的蛋白,属于神经递质转运蛋白家族。 免疫原肽与其他已知蛋白质没有显著同源性。
抗体与各种物种的交叉反应性尚不清楚免疫原序列在小鼠、人和猴中100%保守。

General description

57kda
囊泡GABA转运蛋白(unc-47)同源物是525个氨基酸长的蛋白,属于神经递质转运蛋白家族(1)。 VGAT在将GABA和甘氨酸摄取到突触囊泡中起作用。 由于蛋白与突触囊泡结合,因此VGAT抗体是突触前GABA能和甘氨酸能神经元的极佳标记。

Immunogen

大鼠VGAT羧基末端区域附近的17个氨基酸肽序列(McIntire,S.,1997)。

Other Notes

浓度:请参考批次特异性浓缩物的分析证书。

Physical form

在含有0.1%BSA的PBS缓冲液中的纯化兔多克隆抗体。

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

未找到合适的产品?  

试试我们的产品选型工具.

存储类别

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ (Lot或Batch)字后找到。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

Ricardo Gómez-Nieto et al.
The Journal of comparative neurology, 516(4), 241-263 (2009-07-28)
Geometry of the dendritic tree and synaptic organization of afferent inputs are essential factors in determining how synaptic input is integrated by neurons. This information remains elusive for one of the first brainstem neurons involved in processing of the primary
Phillip R Kramer et al.
Neuroscience, 356, 207-216 (2017-05-28)
Pain is a common complication of herpes zoster (HZ) infection which results from reactivation of a latent varicella zoster virus (VZV). A third of HZ patients' progress to a chronic pain state known as post herpetic neuralgia (PHN), and about
Maria Medalla et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 37(18), 4717-4734 (2017-04-07)
The lateral prefrontal cortex (LPFC) and anterior cingulate cortex (ACC) of the primate play distinctive roles in the mediation of complex cognitive tasks. Compared with the LPFC, integration of information by the ACC can span longer timescales and requires stronger
Mark A Rossi et al.
Nature neuroscience, 19(5), 742-748 (2016-04-05)
The contribution of basal ganglia outputs to consummatory behavior remains poorly understood. We recorded from the substantia nigra pars reticulata (SNR), the major basal ganglia output nucleus, during self-initiated drinking in mice. The firing rates of many lateral SNR neurons
Pablo Henny et al.
The Journal of comparative neurology, 499(4), 645-661 (2006-10-10)
Orexin/hypocretin (Orx) neurons are critical for the maintenance of waking in association with behavioral arousal and postural muscle tone, since with their loss narcolepsy with cataplexy occurs. Given that basal forebrain (BF) neurons project to the hypothalamus and play important

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持