生物来源
rabbit
质量水平
抗体形式
affinity purified immunoglobulin
抗体产品类型
primary antibodies
克隆
polyclonal
纯化方式
affinity chromatography
种属反应性
rat
包装
antibody small pack of 25 μg
制造商/商品名称
Chemicon®
技术
western blot: suitable
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
rat ... Grin1(24408)
特异性
Specific for the NMDAR1 C1 splice variant. AB5046P recognizes the C1 splice insert present in NR1 variants, 1a, 1b, 3a and 3b. {Gorter et al, (1997), "The Role of Alternative Splicing of the NMDAR1 Receptor Subunit in Synaptic Plasticity" Chapter 4, pg 99, in The Ionotropic Glutamate Receptors , Monaghan, D.T. and Weinhold, R.J. (eds), Humana Press, New Jersey) By Western blot the antibody recognizes a protein with molecular weight of 100 kDa.
免疫原
Peptide corresponding to the C-terminus of the rat NMDAR1 C1 splice variant.
应用
Anti-NMDAR1 Splice Variant C1 Antibody is an antibody against NMDAR1 Splice Variant C1 for use in WB.
Research Category
Neuroscience
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
Neurotransmitters & Receptors
Western blot: 1:1,000 using ECL on rat brain lysate.
Immunohistochemistry: 1:1,000.
Optimal working dilutions must be determined by the end user.
Immunohistochemistry: 1:1,000.
Optimal working dilutions must be determined by the end user.
外形
Affinity purified immunoglobulin. Lyophilized from ammonium bicarbonate (5 mM) so some residual salt may also be present. Reconstitute with 50 μL of PBS. Contains no preservatives.
储存及稳定性
Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
11 - Combustible Solids
WGK
WGK 1
K D Holmes et al.
Journal of neurochemistry, 81(6), 1152-1165 (2002-06-18)
The N -methyl-D-aspartate receptor (NMDAR) is a multimeric transmembrane protein composed of at least two subunits. One subunit, NR1, is derived from a single gene and can be subdivided into three regions: the N-terminal extracellular domain, the transmembrane regions, and
Israel Pichardo-Casas et al.
Brain research, 1436, 20-33 (2011-12-27)
In recent years, microRNAs or miRNAs have been proposed to target neuronal mRNAs localized near the synapse, exerting a pivotal role in modulating local protein synthesis, and presumably affecting adaptive mechanisms such as synaptic plasticity. In the present study we
Fadia Ibrahim et al.
Cell reports, 3(2), 301-308 (2013-02-19)
RNA binding proteins (RBPs) have emerged as major causative agents of amyotrophic lateral sclerosis (ALS). To investigate the function of TAF15, an RBP recently implicated in ALS, we explored its target RNA repertoire in normal human brain and mouse neurons.
Pilar Sánchez-Blázquez et al.
The international journal of neuropsychopharmacology, 21(10), 938-948 (2018-06-04)
Several currently available animal models reproduce select behavioral facets of human mania as well as the abnormal glutamatergic neurotransmission and dysregulation of glycogen synthase kinase 3β that accompanies this disease. In this study, we addressed the therapeutic potential of ligands
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