跳转至内容
Merck
CN

AB4326

ISL-1抗体

from rabbit, purified by affinity chromatography

别名:

ISL LIM homeobox 1, ISL1 transcription factor, LIM/homeodomain, ISL1 transcription factor, LIM/homeodomain, (islet-1)

登录 查看组织和合同定价。

选择尺寸

关于此项目

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702

主要文件

查看所有文档
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

产品名称

ISL-1抗体, from rabbit, purified by affinity chromatography

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

horse, human, mouse

species reactivity (predicted by homology)

sheep (based on 100% sequence homology), canine (based on 100% sequence homology), rat (based on 100% sequence homology), equine (based on 100% sequence homology), bovine (based on 100% sequence homology)

technique(s)

immunocytochemistry: suitable
immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

NP_002193

UniProt accession no.

P61371

shipped in

wet ice

target post-translational modification

unmodified

Quality Level

100

Gene Information

human ... ISL1(3670)

相关类别

Biochem/physiol Actions

该抗体可识别ISL-1。
基于100%的序列同源性，预测会与最常见的脊椎动物物种反应。

Analysis Note

通过蛋白质印迹法对K562细胞裂解液进行了评估。

蛋白质印迹分析：0.5 µg/mL的该抗体在10 µg K562细胞裂解液中检测到ISL-1。

Application

ISL-1抗体是一种检测ISL-1（又称ISL LIM同源盒1、ISL1转录因子LIM/同源结构域）的兔多克隆抗体 & 已通过WB & IHC验证。
免疫组化分析：先前批次的1:300稀释液在小鼠胰腺组织中检测到ISL-1。

General description

胰岛因子1（ISL-1）是一种转录因子，在朗格汉斯胰岛的胚胎发生中发挥重要作用。它在肾上腺髓质和背根神经节的神经元亚群、视网膜内核和神经节细胞层、松果体和大脑某些区域中表达。在小鼠胚胎中，缺乏这种基因就无法进行神经管运动神经元的分化。最近，它被确定为心脏祖细胞谱系的标志物，该谱系能够分化为所有3种主要心脏细胞类型：心肌细胞、平滑肌和内皮细胞谱系。
~39 kDa

Immunogen

KLH偶联线性肽，对应于人ISL-1。
表位：ISL-1的内部区域。

Other Notes

浓度：请参考批次特异性浓缩物的检验报告。

未找到合适的产品？  

试试我们的产品选型工具.

存储类别

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

分析证书(COA)

输入产品批号来搜索 分析证书(COA) 。批号可以在产品标签上"批“ （Lot或Batch）字后找到。

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Rustam Esanov et al.
Experimental neurology, 277, 171-177 (2016-01-10)
Among several genetic mutations known to cause amyotrophic lateral sclerosis (ALS), a hexanucleotide repeat expansion in the C9orf72 gene is the most common. In approximately 30% of C9orf72-ALS cases, 5-methylcytosine (5mC) levels within the C9orf72 promoter are increased, resulting in
Joseph A Bisson et al.
Developmental biology, 398(1), 80-96 (2014-12-09)
Wnt proteins regulate cell behavior via a canonical signaling pathway that induces β-catenin dependent transcription. It is now appreciated that Wnt/β-catenin signaling promotes the expansion of the second heart field (SHF) progenitor cells that ultimately give-rise to the majority of
Shuichi Kato et al.
Nagoya journal of medical science, 77(1-2), 253-263 (2015-03-24)
Transplantation of motoneurons (MN) into the peripheral nerve to provide a source of neurons for muscle reinnervation, termed motoneuron integrated striated muscle (MISM), may provide the potential to restore functional muscle activity, when combined with computer-programmed functional electrical stimulation (FES).
Laura I Hudish et al.
Stem cell reports, 14(6), 1033-1043 (2020-05-11)
Human motor neuron (MN) diseases encompass a spectrum of disorders. A critical barrier to dissecting disease mechanisms is the lack of appropriate human MN models. Here, we describe a scalable, suspension-based differentiation system to generate functional human MN diseases in
Zane Zeier et al.
Experimental neurology, 271, 241-250 (2015-06-24)
A hexanucleotide repeat expansion residing within the C9ORF72 gene represents the most common known cause of amyotrophic lateral sclerosis (ALS) and places the disease among a growing family of repeat expansion disorders. The presence of RNA foci, repeat-associated translation products
查看所有相关文献

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持