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Merck
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主要文件

AB3639

Sigma-Aldrich

Anti-Endonuclease G Antibody

Chemicon®, from rabbit

别名:

EndoG

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100 μG
¥3,726.10

¥3,726.10


预计发货时间2025年3月25日详情


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100 μG
¥3,726.10

About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

¥3,726.10


预计发货时间2025年3月25日详情


获取大包装报价

生物来源

rabbit

质量水平

抗体形式

affinity purified immunoglobulin

抗体产品类型

primary antibodies

克隆

polyclonal

纯化方式

affinity chromatography

种属反应性

mouse, rat, human

制造商/商品名称

Chemicon®

技术

western blot: suitable

NCBI登记号

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此商品
E5654SAB2103518SAB3500468
antibody form

affinity purified immunoglobulin

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

purified immunoglobulin

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

mouse

Gene Information

human ... ENDOG(2021)
mouse ... Endog(13804)
rat ... Endog(362100)

Gene Information

human ... ENDOG(2021)
mouse ... Endog(13804)
rat ... Endog(362100)

Gene Information

human ... ENDOG(2021)

Gene Information

human ... ENDOG(2021)

technique(s)

western blot: suitable

technique(s)

ELISA: suitable, immunohistochemistry: suitable, western blot: suitable

technique(s)

western blot: suitable

technique(s)

indirect ELISA: suitable, western blot: suitable

shipped in

wet ice

shipped in

dry ice

shipped in

wet ice

shipped in

dry ice

特异性

Recognizes Endonuclease G (EndoG), a mitochondrion-specific nuclease that translocates to the nucleus and cleaves chromatin DNA during apoptosis. EndoG is specifically activated by apoptotic stimuli and is able to induce nucleosomal fragmentation of DNA independently of caspase and DFF/CAD (1,2).

免疫原

Synthetic peptide corresponding to amino acids 55 to 70 of human EndoG (GGPRGPGELAKYGLP).

应用

Anti-Endonuclease G Antibody is an antibody against Endonuclease G for use in WB.
Research Category
Apoptosis & Cancer
Research Sub Category
Apoptosis - Additional
Western blotting (1-2μg/mL)

Optimal working dilutions must be determined by the end user.

外形

Affinity purified immunoglobulin. Liquid in PBS containing 0.02% sodium azide.

储存及稳定性

Maintain at 2-8ºC for 12 months.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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    Tamara Azarashvili et al.
    International journal of molecular sciences, 17(12) (2016-12-17)
    The translocator protein (TSPO; 18 kDa) is a high-affinity cholesterol-binding protein located in the outer membrane of mitochondria. A domain in the C-terminus of TSPO was characterized as the cholesterol recognition/interaction amino acid consensus (CRAC). The ability of the CRAC
    Shuangping Zhao et al.
    Journal of neuroscience research, 88(8), 1727-1737 (2010-01-16)
    We have shown that generalized seizures produce necrotic neurons with caspase-independent nuclear pyknosis and DNA fragmentation. In this study, we determined the time course of translocation of mitochondrial cytochrome c, apoptosis-inducing factor, endonuclease G, lysosomal cathepsins B and D, and
    Traumatic noise activates Rho-family GTPases through transient cellular energy depletion.
    Chen, FQ; Zheng, HW; Hill, K; Sha, SH
    The Journal of Neuroscience null
    Sathivel Chinnathambi et al.
    Cells, tissues, organs, 187(2), 131-140 (2007-10-17)
    We examined how young and old keratinocytes died from heat stress in vitro. We found that keratinocyte cell death was not due to oxidative stress as neither Mn-SOD nor Cu-Zn-SOD was produced in either young or old heated keratinocytes. Instead
    H-W Zheng et al.
    Cell death & disease, 5, e1262-e1262 (2014-05-31)
    Receptor-interacting protein (RIP) kinases promote the induction of necrotic cell death pathways. Here we investigated signaling pathways in outer hair cells (OHCs) of adult male CBA/J mice exposed to noise that causes permanent threshold shifts, with a particular focus on

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