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Merck
CN
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主要文件

AB3572P

Sigma-Aldrich

Anti-Organic Anion Transporting Polypeptide 2 Antibody, CT, intracellular

Chemicon®, from rabbit

别名:

oatp2, OATP-B1, Brain digoxin carrier protein

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About This Item

UNSPSC代码:
12352203
eCl@ss:
32160702
NACRES:
NA.41

生物来源

rabbit

质量水平

抗体形式

affinity purified immunoglobulin

抗体产品类型

primary antibodies

克隆

polyclonal

纯化方式

affinity chromatography

种属反应性

rat

制造商/商品名称

Chemicon®

技术

ELISA: suitable
western blot: suitable

NCBI登记号

UniProt登记号

运输

dry ice

靶向翻译后修饰

unmodified

基因信息

一般描述

Organic Anion Transporting Polypeptide 2 is an integral membrane protein that mediates the sodium-independent transport of organic ions, cardiac glycosides and thyroid hormones. Oatp2 is highly expressed in brain, liver, and kidney but not expressed in heart, spleen, lung, skeletal muscle, or testis.

特异性

Recognizes rat Organic Ion Transporter 2 Polypeptide 2.

免疫原

A 12 amino acid peptide sequence near the cytoplasmic, C-terminus of rat OATP2. The immunogen shows no significant sequence similarity to other OATPs or other proteins.

应用

Detect Organic Anion Transporting Polypeptide 2 using this Anti-Organic Anion Transporting Polypeptide 2 Antibody, C-terminus, intracellular validated for use in ELISA & WB.
Western blot: 1-10 μg/mL using ECL. Rat OATP2 is approximately 75 kD in brain and liver (Noe et al. 1997).

ELISA: 0.5-1.0 μg/mL using 1 μg/mL control peptide per well.

Optimal working dilutions must be determined by the end user.

外形

Affinity purified immunoglobulin. Liquid in PBS, containing 0.1% BSA.

其他说明

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

法律信息

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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储存分类代码

12 - Non Combustible Liquids

WGK

WGK 2

闪点(°F)

Not applicable

闪点(°C)

Not applicable


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Camilla A Thorling et al.
Journal of biomedical optics, 18(10), 101306-101306 (2013-07-03)
The liver is important in the biotransformation of various drugs, where hepatic transporters facilitate uptake and excretion. Ischemia-reperfusion (I/R) injury is a common occurrence in liver surgery, and the developing oxidative stress can lead to graft failure. We used intravital

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