推荐产品
生物来源
rabbit
质量水平
抗体形式
serum
抗体产品类型
primary antibodies
克隆
polyclonal
种属反应性
human
制造商/商品名称
Chemicon®
技术
western blot: suitable
NCBI登记号
UniProt登记号
运输
dry ice
靶向翻译后修饰
unmodified
基因信息
human ... BCL2L1(598)
一般描述
Bcl-XL is one of the anti-apoptotic members of the Bcl-2 family of apoptosis regulators and is overexpressed in many human cancers. Studies by Dr. Haldar and his associates suggest that microtubule damaging drugs like Taxol or 2-methoxyestradiol induce phosphorylation of Bcl-XL at serine 62 by kinases such as Jun and this allows those cells to die by apoptosis.
特异性
AB3116 is specific for the Bcl-xL phosphorylated on serine 62. It does not recognize the unphosphorylated form of the protein.
免疫原
Epitope: Phospho-specific
Synthetic phosporylated peptide corresponding to a sequence encompassing serine 62 of human Bcl-xL conjugated to KLH.
应用
Detect Bcl-xL using this Anti-Bcl-xL Antibody, Phospho-specific validated for use in WB.
Immunoblotting: Recommended dilution is 1:100
Optimal dilutions must be determined by end-user.
Optimal dilutions must be determined by end-user.
Research Category
Apoptosis & Cancer
Apoptosis & Cancer
Research Sub Category
BCL2 & Inhibition
Tumor Markers
BCL2 & Inhibition
Tumor Markers
外形
Liquid rabbit serum containing no preservatives.
储存及稳定性
Maintain at -80°C for up to 12 months from date of receipt. Avoid repeated freeze/thaw cycles.
法律信息
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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