AB2283
抗-Tbr2抗体
from rabbit, purified by affinity chromatography
别名:
eomesodermin (Xenopus laevis) homolog, eomesodermin homolog (Xenopus laevis), t box, brain, 2
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关于此项目
UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
immunohistochemistry
Species reactivity:
human, mouse
Citations:
36
Technique(s):
immunohistochemistry: suitable
Uniprot accession no.:
产品名称
抗-Tbr2抗体, from rabbit, purified by affinity chromatography
antibody product type
primary antibodies
biological source
rabbit
conjugate
unconjugated
antibody form
affinity isolated antibody
clone
polyclonal
purified by
affinity chromatography
species reactivity
human, mouse
technique(s)
immunohistochemistry: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... EOMES(8320)
mouse ... Eomes(13813)
Analysis Note
对照
人脑组织
人脑组织
通过免疫组化在人脑组织中进行了评估。
免疫组化分析： 来自先前批次的抗Tbr2抗体的1:300稀释液在小鼠和人脑组织中检测到Tbr2。
免疫组化分析： 来自先前批次的抗Tbr2抗体的1:300稀释液在小鼠和人脑组织中检测到Tbr2。
Application
研究子类别
发育神经科学
发育神经科学
研究类别
神经科学
神经科学
该抗Tbr2抗体经过验证可用于IH中，以检测Tbr2。
Biochem/physiol Actions
该抗体可识别Tbr2。
Disclaimer
除非我们的产品目录或产品附带的其他公司文档另有说明，否则我们的产品仅供研究使用，不得用于任何其他目的，包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。
General description
Tbr2（T结构域转录因子）是保守的蛋白家族的成员，该家族共享一个共同的DNA结合结构域，T-box。T-box基因编码参与发育过程调控的转录因子。 Trb2已显示在新皮层的发育中起作用，并在放射状胶质向有丝分裂后投射神经元的分化途径中起作用。
Immunogen
对应于小鼠Tbr2的KLH偶联线性肽。
表位：内部结构域
Other Notes
浓度：请参考批次特异性浓缩物的检验报告。
Physical form
亲和纯化
纯化的兔多克隆抗体，溶于含有0.1 M Tris-甘氨酸（pH 7.4）、150 mM NaCl和0.05％叠氮化钠的缓冲液中。
Preparation Note
自发运之日起，在 2-8°C 条件下可稳定保存1年
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存储类别
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Dan Xu et al.
PLoS biology, 16(12), e2006613-e2006613 (2018-12-20)
Mutations of WD repeat domain 62 (WDR62) lead to autosomal recessive primary microcephaly (MCPH), and down-regulation of WDR62 expression causes the loss of neural progenitor cells (NPCs). However, how WDR62 is regulated and hence controls neurogenesis and brain size remains
Joanna Yeung et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 36(35), 9057-9069 (2016-09-02)
Pax6 is a prominent gene in brain development. The deletion of Pax6 results in devastated development of eye, olfactory bulb, and cortex. However, it has been reported that the Pax6-null Sey cerebellum only has minor defects involving granule cells despite
Livia Goto-Silva et al.
BMC developmental biology, 19(1), 3-3 (2019-03-08)
Organoid cultivation in suspension culture requires agitation at low shear stress to allow for nutrient diffusion, which preserves tissue structure. Multiplex systems for organoid cultivation have been proposed, but whether they meet similar shear stress parameters as the regularly used
Teresa Guillamon-Vivancos et al.
Cerebral cortex (New York, N.Y. : 1991), 29(3), 1121-1138 (2018-02-08)
How the variety of neurons that organize into neocortical layers and functional areas arises is a central question in the study of cortical development. While both intrinsic and extrinsic cues are known to influence this process, whether distinct neuronal progenitor
Melanie Schoof et al.
Acta neuropathologica communications, 7(1), 199-199 (2019-12-07)
CREB (cyclic AMP response element binding protein) binding protein (CBP, CREBBP) is a ubiquitously expressed transcription coactivator with intrinsic histone acetyltransferase (KAT) activity. Germline mutations within the CBP gene are known to cause Rubinstein-Taybi syndrome (RSTS), a developmental disorder characterized
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