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UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Clone:
polyclonal
Species reactivity:
mouse
Application:
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Technique(s):
ELISA: suitable
immunohistochemistry: suitable
western blot: suitable
immunohistochemistry: suitable
western blot: suitable
Citations:
19
Uniprot accession no.:
产品名称
Anti-Integrin α5 Antibody, serum, Chemicon®
biological source
rabbit
antibody form
serum
antibody product type
primary antibodies
clone
polyclonal
species reactivity
mouse
manufacturer/tradename
Chemicon®
technique(s)
ELISA: suitable
immunohistochemistry: suitable
western blot: suitable
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Quality Level
Gene Information
human ... ITGA5(3678)
Application
Detect Integrin α5 using this Anti-Integrin α5 Antibody validated for use in ELISA, WB, IH.
ELISA.
Western blotting: (The antigen should be separated in SDS-PAGE under reducing conditions
and does not react with non-reduced sample.): 1:5,000.
Immunohistochemistry/Immunofluorescence: 1:1,000.
Optimal working dilutions must be determined by the end user.
Western blotting: (The antigen should be separated in SDS-PAGE under reducing conditions
and does not react with non-reduced sample.): 1:5,000.
Immunohistochemistry/Immunofluorescence: 1:1,000.
Optimal working dilutions must be determined by the end user.
Research Category
Cell Structure
Cell Structure
Research Sub Category
Integrins
Integrins
Biochem/physiol Actions
Specific for alpha5 integrin as determined by Western blotting.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Immunogen
Recombinant fragment of mouse alpha5 integrin (Holers et al. 1989) corresponding to amino acid residues 655-880 of the human protein (Argraves 1987). This region of the molecule is extracellular and is included in the heavy chain (120 kDa).
Physical form
Whole rabbit serum. Liquid, with 0.02% sodium azide.
Preparation Note
Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Legal Information
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
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存储类别
10 - Combustible liquids
Nanopatterning reveals an ECM area threshold for focal adhesion assembly and force transmission that is regulated by integrin activation and cytoskeleton tension.
Coyer, SR; Singh, A; Dumbauld, DW; Calderwood, DA; Craig, SW; Delamarche, E; Garcia, AJ
Journal of Cell Science null
CCN2 (Connective Tissue Growth Factor) is essential for extracellular matrix production and integrin signaling in chondrocytes.
Nishida, T; Kawaki, H; Baxter, RM; Deyoung, RA; Takigawa, M; Lyons, KM
Journal of Cell Communication and Signaling null
Opposing effects of collagen I and vitronectin on fibronectin fibril structure and function.
Gildner, CD; Roy, DC; Farrar, CS; Hocking, DC
Matrix Biology null
Oumou Goundiam et al.
Cell biology international, 36(3), 311-319 (2011-11-11)
In the highly metastatic B16F10 melanoma cell line, activation of the signalling molecules that promote cell proliferation and survival on conventional adhesive culture dishes may also be responsible for the growth and resistance to anoikis of aggregates on a non-adhesive
Recombinant fibronectin matrix mimetics specify integrin adhesion and extracellular matrix assembly.
Roy, DC; Hocking, DC
Tissue Engineering: Part A null
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